PUBLICATIONS

1. Dressler, G.R. and Fraser, N.W. (1987). DNA Sequences Downstream of the Adenovirus Type 2 Fiber Polyadenylation Site Contain Transcription Termination Signals.  J. Virol. 61, 2770-2776.

2. Dressler, G.R., Rock, D.L., Fraser, N.W.(1987). Latent Herpes Simplex  Virus Type 1 DNA is not Extensively Methylated in vivo . J. Gen. Virol. 68, 1761-1765.

3.  Chowdhury, K., Dressler, G.R., Breier, G., Deutsch, U., Gruss, P. (1988) The primary structure of the murine mKr2 gene and its specific expression in adult and developing neurons.  EMBO J. 7, 1345-1353.

4.  Breier, G., Dressler, G.R., Gruss, P. (1988) Primary structure and developmental expression pattern of Hox 3.1, a member of the murine Hox 3 homeobox gene cluster.  EMBO J. 7, 1329-1336.

5.  Deutsch, U., Dressler, G.R., Gruss, P. (1988) Pax 1, a member of a paired box homologous murine gene family, is expressed in segmented structures during development.  Cell 53, 617-625.

6.  Dressler, G.R. and Gruss, P. (1988) Do multi-gene families regulate vertebrate development?  Trends in Genetics  4, 214-219

7.  Dressler, G.R., Deutsch, U., Balling, R., Simon, D., Guenet, J-L., Gruss, P. (1988) Murine genes with homology to Drosophila  segmentation genes. Development  104 supplement, 181-186.

8.  Duprey, P., Chowdhury, K., Dressler, G.R., Balling, R., Simon, D., Guenet, J.-L.,    Gruss, P. (1988) A mouse gene homologous to the Drosophila gene caudal is expressed in epithelial cells from the embryonic intestine.  Genes & Develop. 2, 1647-1654.

9.  Dressler, G. R. and Fraser, N. W. (1989) The Adenovirus-2 major late transcription termination region contains multiple functional elements.  J. Gen. Virol.  70, 1337-1345.

10. Dressler, G. R. (1989) An update on the vertebrate homeobox.  Trends in Genetics  5, 129-131.

11. Dressler, G. R. and Gruss, P. (1989) Anterior boundries of Hox gene expression in mesoderm derived structures correlate with the linear gene order along the chromosome.  Differentiation 41, 193-201.

12. Püschel, A. W., Balling, R., Dressler, G. R., Gruss, P. (1989) The Hox 1.1 promoter directs expression to a specific region of the embryo in transgenic mice. in Current Communications in Molecular Biology: Molecular Genetics of Early Drosophila and Mouse Development. (M. R. Capecchi, ed.)pp91-95.

13. Dressler, G.R., Deutsch, U., Chowdhury, K., Nornes, H., Gruss, P. (1990) Pax2 a new murine paired box containing gene and its expression in the developing excretory system. Development 109, 787-795.

14. Nornes, H., Dressler, G. R., Knapik, E. W., Deutsch, U., Gruss, P. (1990) Spatially and temporally restricted expression of Pax2 during murine neurogenesis.  Development  109, 797-809.

15. Schoeller, H., Dressler, G. R., Balling, R., Rohdewold, H., Gruss, P. (1990)  Oct4, a germ line specific transcription factor mapping to the mouse t-complex.  EMBO J. 9, 2185-2195.

16. Dressler, G. R.  and Douglass, E. C. (1992) Pax-2 is a DNA binding protein expressed in embryonic kidney and Wilms' tumor.  Proc. Natl. Acad. Sci. USA 89, 1179-1183.

17. Pueschel, A. W., Westerfield, M., Dressler, G. R. (1992) Comparative analysis of Pax-2 protein distributions during neurulation in mice and zebrafish.  Mech. Develop. 38, 197-208.

18. Rothenpieler, U. W. and Dressler, G. R. (1993) Pax-2 is required for mesenchyme to epithelium conversion during kidney development. Development  119, 711-720.

19. Phelps, D. E., Dressler, G. R. (1993) Aberrant expression of Pax-2 in Danforth's short tail (Sd) mice. Develop. Biol. 157, 251-258.

20. Rothenpieler, U.W. and Dressler, G. R. (1993) Differential Distribution of Oligodeoxynucleotides in Developing Organs with Epithelial and Mesenchymal Interactions. Nucleic Acids Res.  21, 4961-4966.

21. Dressler, G. R., Wilkinson, J. E., Rothenpieler, U. W., Patterson, L. T., Williams, L., Westphal, H. (1993) Deregulation of Pax-2 expression in transgenic mice generates severe kidney abnormalitites. Nature  362, 65-67.

22. Dressler, G.R. (1994) The pros and cons of c-ret.  Current Biol. 4, 354-356.

23. Patterson, L.T. and Dressler, G. R. (1994) Regulation of Kidney Development: new insights from an old model.  Curr. Opin. Genet. Develop. 4, 696-702.

24. Dressler, G. R. (1995) Developmental Control Genes, in Molecular Nephrology (D. Schloendorff and J. Bonventre eds.) Marcel Dekker, New York,  pp1-13.

25. Ryan, G., Steele-Perkins, V., Morris, J., Rauscher, F. J. III, Dressler, G.R. (1995) Repression ofPax-2 byWT1 during normal kidney development.  Development  121, 867-875.

26. Dressler, G. R. (1995) Transcription factors in renal development: the WT1 and Pax-2 story. Sem. Nephrol. 15, 263-271.

27. Dressler, G. R. (1995) The genetic control of renal development.  Curr. Opin. Hyper. Nephrol. 4, 253-257.

28. Gnarra, J. R. and Dressler, G. R.  (1995) Expression of Pax-2 in renal cell carcinoma and growth inhibition by antisense oligonucleotides. Cancer Research.55, 4092-4098.

29. Torres, M., Gomez-Pardo, E., Dressler, G. R. and Gruss, P. (1995) Pax-2 controls multiple steps in urogenital development. Development  121, 4057-4065.

30. Phelps, D.E. and Dressler, G. R. (1996) Identification of NovelPax-2 binding sequences by chromatin immunoprecipitation. J. Biol. Chem. 271, 7978-7985.

31. Dressler, G. R. (1996) Pax-2, kidney development and oncogenesis.  Med. Ped. Oncol. 27, 440-444.

32. Winyard, P.J.D., Risdon, A.R., Sams, V.R., Dressler, G.R. and Woolf, A.S. (1996) The Pax2 transcription factor is overexpressed in cystic and hyperproliferative dysplastic epithelia in human kidney malformations.  J. Clin. Invest.   98, 451-459.

33. Lechner, M. S. and Dressler, G. R. (1996) Mapping of Pax-2 transcription activation domains. J.Biol. Chem. 271, 21088-21093.

34. Dehbi, M., Gharemani, M., Lechner, M., Dressler, G. and Pelletier, J. (1996) The paired-box transcription factor, PAX2, positively modulates expression of the Wilms’ tumor suppressor gene (WT1).  Oncogene 13, 447-453.

35. Vega, Q.C., Worby, C.D., Lechner, M.S., Dixon, J.E. and Dressler, G.R. (1996)  Glial derived neurotrophic factor is a ligand for RET and promotes kidney morphogenesis.  Proc. Natl. Acad. Sci. USA.93, 10657-10661

36. Dressler, G. R. (1997)  Genetic control of kidney development.  Adv. Nephrol. 26, 1-17.

37. Valentini, R., Brookhiser, W. T., Park, J., Yang, T., Briggs, J., Dressler, G.R., and Holzman, L.B. (1997) Post-translational processing and renal expression of mouse indian hedgehog cDNA. J. Biol. Chem. 272, 8466-8473.

38. Lechner, M. S. and Dressler, G. R (1997) The molecular basis of embryonic kidney development.  Mech. Develop. 62, 105-120.

39. Leavey, S.F., Arend, L.J., Dare, H., Dressler, G.R., Briggs, J.P. and Margolis, B.L. (1998) Expression of Grb7 growth factor receptor signaling protein in kidney development and in the adult kidney. Am. J. Physiol.  275, F770-F776.

40. Cho, E. A., Patterson, L.P., Brookhiser, W.T., Mah, S., Kintner, C. and Dressler, G.R.  (1998) Expression and function of cadherin-6 in the developing kidney.  Development  125, 803-812.

41. Cho, E.A. and Dressler, G.R.  (1998) Mouse Tcf-4 binds b-catenin and is expressed in distinct regions of the developing brain and limbs.  Mech. Develop. 77, 9-18.

42. Tang, M.J., Worley, D., Sanicola, M. and Dressler, G.R.  (1998)  The RET-Glial Cell-derived Neurotrophic Factor (GDNF) pathway stimulates migration and chemoattraction of epithelial cells. J. Cell Biol.  142, 1337-1345.

43. Weiss, J.B., Von Ohlen, T., Mellerick, D.M., Dressler, G., Doe, C.Q. and Scott, M.P. (1998).  Dorsoventral patterning in the Drosophila central nervous system: the intermediate neuroblasts defective homeobox gene specifies intermediate column identity.  Genes & Dev. 12, 3591-3602.

44. Yang, Y., Jeanpierre, C., Dressler, G.R., Lacoste, M., Niaudet, P. and Gubler, M.-C. (1999) WT1 and Pax-2 podocyte expression in Denys-Drash syndrome and isolated diffuse mesangial scelrosis.  Am J. Pathol 154, 181-192.

45. Dressler, G.R. (1999)  Kidney development branches out.  Dev. Genetics 24, 189-193.

46. Schwarz, M., Alvarez-Bolado, G., Dressler, G., Urbanek, P., Busslinger, M., and Gruss, P. (1999) Pax2/5 and Pax6 subdivide the early neural tube into three domains.   Mech. Dev. 82, 29-39

47. Dressler, G. R. and Woolf, A. S. (1999) Pax2 in development and renal disease.  Int. J. Dev. Biol.  43, 463-468.

48. Ostrom, L., Tang, M.-J., Gruss, P., and Dressler, G.R. (2000)  Reduced Pax2 gene dosage increases apoptosis and slows the progression of renal cystic disease.   Dev. Biol. 219, 250–258

49. Mah, S.P., Saueressig, H., Goulding, M., Kintner, C., and Dressler, G.R. (2000) Kidney development in cadherin-6 mutants: delayed mesenchymal-to-epithelial conversion and loss of nephrons. Dev. Biol.  223, 38-53.

50. Lechner, M.S. Levitan, I. and Dressler, G.R.  (2000) PTIP, A novel BRCT-domain protein interacts with Pax2 and is associated with active chromatin. Nucleic Acids Res. 28, 2741-2751.

51. Dressler, G.R. (2001) The Development of the Excretory System. In: Mouse Development (J. Rossant and P. Tam, eds.) Academic Press, NY, pp395-420.

52. Brophy, P.D, Ostrom, L., Lang, K.M. and Dressler, G.R. (2001) Regulation of Ureteric Bud Outgrowth by Pax2 Dependent Activation of the Glial Derived Neurotrophic Factor Gene.  Development  128, 4747-4756.

53. Cai, Y., Lechner, M.S., Nihalani, D., Prindle, M., Holzman, L.B. and Dressler, G.R. (2002) Phosphorylation of Pax2 by the c-Jun N-terminal kinase and enhanced Pax2 dependent transactivation.  J. Biol Chem. 277, 1217-1222.

54. Tang, M.J., Cai, Y., Tsai, S.J., Wang, Y.K. and Dressler, G.R. (2002) Ureteric Bud Outgrowth in Response to RET Activation is Mediated by Kinase. Dev. Biol. 243, 128-136.

55. Silberstein, G. B, Dressler, G.R. and Van Horn, K. (2002) Expression of the Pax2 oncogene in human breast cancer and its role in progesterone dependent mammary growth.  Oncogene 21, 1009-1016.

56. Hoffmeister, A., Ropolo, A.,Vasseur, S., Mallo, G.V., Bodeker, H., Ritz-Laser, B., Dressler, G.R., Vaccaro, M.I., Dagorn, J.C., Moreno, S. and Iovanna, J.L. (2002) The HMG-I/Y-related protein p8 binds to p300 and Pax2 trans-activation-domain interacting protein to regulate the trans-activation activity of the Pax2A and Pax2B transcription factors on the glucagon gene promoter. J. Biol. Chem. 277, 22314-22319.

57. Dressler, G.R. (2002) Tubulogenesis in the developing mammalian kidney.  Trends Cell Biol. 12, 390-395.

58. Cho, E.A. and Dressler, G.R. (2003) The Formation and Development of Nephrons.  In: The kidney: Normal Development to Congenital Abnormalities (P. D. Vize, A. S. Woolf, J. B. L. Bard, eds) Academic Press, pp195-210.

59. Cho, E.A., Prindle, M.J. and Dressler, G.R. (2003) The BRCT domain protein PTIP is required for progression through mitosis. Mol. Cell. Biol. 23, 1666-1673

60. Cai, Y., Brophy, P., Levitan, I. and Stefano, S. and Dressler, G.R. (2003) Groucho suppresses Pax2 transactivation by inhibition of JNK mediated phosphorylation.  EMBO J.22, 5522-5529

61. Brophy, P.D., Lang, K.M., and Dressler, G.R. (2003) The secreted frizzled related protein SFRP2 is a target of the Pax2 transcription factor.  J. Biol. Chem.  278, 52401-52405.

62. Patel, S. R. and Dressler, G.R. (2004) Expression of Pax2 in the intermediate mesoderm is regulated by YY1.  Dev. Biol. 267, 505-516.

63. Dressler, G. R. (2004) Cell Lineages and Stem cells in the Embryonic Kidney.  In: Handbook of Stem Cells, Vol.1: Embryonic Stem Cells (R. Lanza, ed.) Elsevier Science, San Diego, CA, p335-344.

64. Levitan, I., Ullenbruch, M., Phan, S.H., Park, J.M. and Dressler, G.R. (2005) Kielin/Chordin-like protein (KCP), a novel enhancer of BMP signaling attenuates renal fibrotic disease.  Nature Medicine, 11, 387-393 (featured in news and views p.373)

65. Nephrogenic factors promote differentiation of mouse embryonic stem cells into renal epithelia.  J. Am. Soc. Nephrol. 16, 3527-3534.

66. Patel, S. R. and Dressler, G. R. (2005) BMP signaling in development and disease.  Trends in Mol. Med. 11, 512-518.

67. Dressler, G. R. (2006) Cell lineages and stem cells in the embryonic kidney.  In: Essentials of Stem Cell Biology (R. Lanza, ed.)  Elsevier Science, San Diego, CA, p227-236.

68. Lin, J., Patel, S. R., Wang, M. and Dressler, G.R. (2006) The cysteine rich domain protein KCP suppresses TGF-b/Activin signaling in renal epithelia.  Mol. Cell. Biol. 26, 4577-4585.

69. Dressler, G. R. (2006) The cellular basis of kidney development.  Ann. Rev. Cell Dev. Biol. in press.

70. Self, M., Lagutin, O., Bowling, B., Hendrix, J., Cai, Y., Dressler, G. R. and Oliver, G. (2006)  The Six2 gene is required for suppression of inductive signals and progenitor cell renewal in the developing kidney.  EMBO J, in press

72. Dressler, G.R. (2006) Stem cells in kidney development and regeneration.  Prog. Tissue Eng., in press

73. Clarke, J. C., Patel, S. R., Raymond, R. M., Andrew, S., Robinson, B. G., Dressler, G. R. and Brophy, P. D. (2006) Pax2 regulates the expression of c-Ret during branching morphogenesis in the mammalian kidney. Hum. Mol. Genetics, in press.

74. Kim, D, Wang, M., Cai, Q., Brooks, H. and Dressler, G.R. (2006) The Pax2 Interacting Protein PTIP is Required for Urine Concentration and Osmotolerance in Collecting Duct Epithelia.  Submitted

75. Kim, D. and Dressler, G. R. (2006)  Inhibition of epithelial cell migration and ureteric bud remodeling by the phosphotidylinositol phosphatase PTEN.  submitted

76. Patel, S.R., Levitan, I. and Dressler, G.R. (2006) The BRCT-domain containing protein PTIP interacts with a histone H3 lysine 4 methyltransfease complex to regulate development.  submitted.

77. Cho, Y.W., Hong, T., Hong, S.H., Yu, H., Kim, D., Guszczynski, T., Dressler, G.R., Copeland, T., Kalkum, M. and Ge, K. (2006) BRCT domain-containing PTIP associates with a Set1/Trithorax like histone methyltransferase complex to regulate PPARg expression. submitted

76. Gong, K.Q., Yallowitz, A.R., Sun, H., Dressler, G.R. and Wellik, D.M. (2007) Physical association of a Hox-Eya-Pax complex at enhancer sequences regulates expression of early patterning genes in the developing kidney.  Mol. Cell Biol. in press.

77.Viana, R., Batourina, E., Hunag, H., Dressler, G.R., Behringer, R.R., Kobayashi, A., Shapiro, E., Hensle, T. and Mendelsohn, C. (2007) The development of the bladder trigone, the center of the anti-reflux mechanism.  Development, in press

78.Patel, S.R., Kim, D., Levitan, I. and Dressler, G.R. (2007) The BRCT-domain containing protein PTIP interacts with a histone H3 lysine 4 methyltransferase complex to regulate development.  submitted.

79.Feng, M and Dressler, G.R. (2007) Drosophila PTIP interacts with the Polycomb/Trithorax pathways and is essential for development.  submitted.

80. Kim, D. and Dressler, G.R. (2007) An essential role for PTIP in maintaining embryonic stem cell pluripotency. submitted.

81. Prindle, M., Patel, S.R., and Dressler, G.R. (2007) Characterization of cell growth and the DNA damage response in PTIP mutant fibroblasts. submitted.

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