Lloyd M. Stoolman, M.D.
Associate Professor of Pathology
Campus Address:
MED Sci I 4224 0602
1301 Catherine Road
Ann Arbor, Michigan 48109-0602
Phone: 734/936-2459
stoolman@path.med.umich.edu
Departmental Annual Report
Brief Biography
Dr. Stoolman received his undergraduate degree from Princeton University, Princeton, New Jersey, in 1972 and his M.D. from the University of California San Francisco (UCSF) in 1977. After an internship and residency in Anatomic Pathology and Laboratory Medicine at UCSF from 1977-1982, including a Chief Residency in Laboratory Medicine, he took a fellowship at UCSF in Anatomy/Cell Biology during 1982-1983.
In 1983, Dr. Stoolman joined the University of Michigan Department of Pathology as an Assistant Professor and Attending Physician for the Flow Cytometry Laboratory. In 1987, he became the Co-Director of the Clinical Flow Cytometry Laboratory. He was promoted to the rank of Associate Professor in 1991. Among many other responsibilities, from 1996 to the present, Dr. Stoolman has been the Director of the Laboratory Sequence in General Pathology for Dental and Graduate Students, where he has developed a Web-based interactive courseware for that Laboratory Sequence.
Dr. Stoolman’s major clinical and research interests are in the areas of hematology, flow cytometry, and immunopathology. He is the Principal Investigator for several current NIH projects, as well as numerous other NIH projects since 1984. He has performed editorial roles for many scientific publications and is currently an Associate Editor for the Journal of Immunology.
Research Interests
Our principle focus is the study of lymphocyte recirculation and migration. Current projects include: (1) the functional characterization of the lymphocyte and endothelial receptors which mediate migration into lymphoid organs and sites of chronic inflammation; (2) investigation of the role of lymphocyte homing receptors in the hematogenous dissemination of lymphoid malignancies; and (3) investigation of the role of migration. Investigators will have the opportunity to study a variety of general topics in cell biology, including mechanisms of intercellular adhesion, the biology of mammalian carbohydrate-binding molecules (lectins), the molecular basis of organ selective lymphocyte recirculation, cell-extracellular matrix interactions, the metastatic process and mechanisms of immunologically-mediated tumor cell lysis. Investigators will be exposed of a wide variety of techniques in cell and cancer biology, including automated flow cytometry, hybridoma technology, tissue culture, in vivo and in vitro measurements of cellular migratory activity and quantitative measurements of the metastatic process.