University of Michigan Hospitals
Apheresis Service
Name:_____________________________________________________ Location: _______________________
CPI#:___________________________________ Age: __________________(M/F)___________________
House Officer (Name/pager): _________________________________________________________________
Attending (Name/pager) _____________________________________________________________________
Procedure Requested: ______________________________________________________________________
Reason/Recent PMH: _______________________________________________________________________
__________________________________________________________________________________________
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Medical History: BP: _____________Pulse: _______________Height: _______________ Weight: ____________
Allergies: Hx_________________________________ Transfusion?/Rxn?:________________________________
Neuro: alert/cooperative _______________________________________________________________________
Cardiac: ___________________________________________________________________________________
Pulmonary: _________________________________________________________________________________
Renal: _____________________________________________________________________________________
Hematology: Bleeding risk with citrate/plt loss? ______________________________________________________
Venous Access (circle/see back): __________Peripheral __________Dialysis Catheter ________ A-V fistula (CRF)
Pertinent Laboratories:
ABO/Rh
CBC: Electrolytes: PT/PTT
Total Protein
Albumin
Ionized Ca++
Other (ex LDH): _________________________________________________________________________________
______________________________________________________________________________________________
Medications**: _________________________________________________________________________________
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**STOPPED: ACE-Inhibitors (Lotensin/Benazepril, Capoten/Captopril, Vasotec/ Enalopril, Monopril/ Fosinopril, Zestril/Prinivil/Linsinopril, Accupril/Quinapril, Univasc/Moesipril, Altace/Ramipril, Movik/Trandolopril)
Diabetic, patient receiving insulin? eat prior to procedure? (risk for hypoglycemia)
Other: Hold next dose until after procedure, since these drugs may be removed with TPEX or may aggravate patient’s medical condition. For example, try holding antihypertensives since hypotension already risk of TPEX.
Protein-bound Drugs: Dilantin, Valproic Acid, Vincristine, Cisplatin, Digitoxin, Warfarin, Diuretics, Synthetic Penicillin, Oral hypoglycemics,
Immune-based Drugs: thymoglobulin, ATGAM, IVIgG, etc..
Pheresis Orders
| Emergent (As Soon as Possible) | Urgent (within 24 hours) |
| Acute TTP/HUS | Recovering TTP/HUS |
| Symptomatic Hyperviscosity | Acute Guillian-Barre Syndrome |
| Symptomatic Hyperleukocytosis (AML) |
Asymptomatic Hyperviscosity plasma viscosity >4 or IgM>3gm |
Emergent (As Soon As Possible) Urgent (within 24 hours)
Acute TTP/HUS recovering TTP/HUS
Symptomatic Hyperviscosity Acute Guillain-Barre Syndrome
Symptomatic Hyperleukocytosis (AML) Asymptomatic Hyperviscosity
Thrombocytosis (>750K) with bleeding plasma viscosity>4 or IgM>3gm
Or thrombosis or platelets >1.5million Acute Vascular Rejection Kidney
Goodpastures with active pulmonary hemorrhage Bx + or PRA+ or crossmatch+
Acute Vascular Rejection Heart (biopsy +) FSGS post-kidney transplant
Venous Access
Peripheral Access: Central access Required
1. Patient alert, cooperative, adequate Poor venous access, intubated,
bilateral anticubital access (16 gauge needles) noncooperative, daily procedures
**placed by apheresis nurses NOT floor!! **Require: dialysis double lumen catheter
2. A-V fistula in chronic dialysis patient Sorenson or Quintan dialysis catheter
Therapeutic Apheresis/Cytopheresis
Indication: Replacement: Frequency Laboratories
TTP/HUS FFP/CPP q Day ABO type, pre-CBC, LDH,Bun/Cr
Acute rej. Liver 2 liters FFP q Day x 3 (Pre-HLA, ABO if indicated)*
Goodpastures with + albumin
Active hemorrhage 1 plasma vol q O Day Pre/post Fibr
TPEX + bleeding* Pre/post Fibr
Waldenstroms qODay x 3-6 Pre/Post Fibr,IgM,viscosity,TP,alb
FSGS 3 q wk x 9-10 Pre/Post Fibr
TPEX, elderly 100% albumin q O Day Pre/Post Fibr,TP,alb
TPEXw/¯ ¯ TP 1 plasma vol Pre/post Fibr, alb
(TPEX w/¯ ¯ Na+)* Pre/Post Fibr
MG,GBS,CIDP q O Day Pre/Post Fibr
Trnsplt Rejection qDx2,qoDx3 Pre/Post Fibr
Goodpastures saline/albumin q O Day (!) Pre/Post Fibr
Cryoglobulin 1 plasma vol 1-2x* Pre/Post Fibr, cryocrit
Multiple Myeloma q O D 1-2x Pre/Post Fibr, TP, alb, Quant. Ig
[G/A/M] & viscosity (if needed)
Sickle Cell* LP-RBC (Adsol)
Acute Chest 10-14 days old Current Type & Cross
Stroke Sickedex neg Once only Pre/Post CBC, ionized Ca++
Priapism Final Hct=30% Pre/Post Hgb electrophoresis
FCR=30% Post K+
Cytoreduction Pre/Post CBC (w diff-WBC)
AML/rare ALL* None Once Post WBC&diff –bag (WBC)
Thrombocytosis 2 blood vol Post Plt cnt-bag (Plt reduct)
Polycythemia
*call BB attending
Form HO2 Revision 1/2004