Clinical
Interests:
Molecular
Pathology; RT-PCR based and DNA sequence based assays for clinical oncology
and bone marrow transplant services.
Research
Interests:
DNA
REPAIR AND GENOMIC STABILITY
1. How DNA
repair pathways both prevent, and cause, chromosomal translocations
during the development and progression of cancer.
2. Elucidating
roles of the Mre11 DNA repair complex in numerous aspects of mammalian
biology, including development, immunity, cancer resistance, and aging.
3. Roles
of DNA repair pathways in gene amplification, especially during the
acquisition of cancer chemotherapy resistance.
SPECTRAL
KARYOTYPING (SKY) TECHNOLOGY
1. Furthering
the use of SKY technology (multicolor chromosome painting) to decipher
complex karyotypes in Human cancers.
2. Identifying
novel recurrent cytogenetic changes for use in the diagnosis and prognosis
of certain cancers.
Brief
Biography:
Dr.
Ferguson received a Ph.D. in Molecular Biology (1996) and an M.D. (1997)
from Cornell University Medical College. He trained in Anatomic and
Clinical Pathology at the Brigham and Women's Hospital, Department of
Pathology, Boston, Massachusetts (1997-2000), and conducted postdoctoral
research in the laboratory of Dr. Frederick Alt, Harvard Medical School
(1999-2003). Dr. Ferguson was appointed as Instructor at Brigham and
Women's Hospital, Department of Pathology for the period 2000-2003.
He received the Young Investigator Award, with Distinction from the
Academy of Clinical Laboratory Physicians and Scientists in 2000 and
2001. In September 2003, he joined the faculty of the Department of
Pathology as Assistant Professor, as part of the University of Michigan
Medical School's Biomedical Scholars Program.
Dr.
Ferguson is board certified in Clinical Pathology. |
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