Jay L. Hess, M.D., Ph.D. Carl V. Weller Professor and Chair Campus Address: M5240 Med Sci I 1301 Catherine Ann Arbor, Michigan  48109-0602 Phone: 734/763-6384 Fax: 734/763-4782 jayhess@umich.edu

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Clinical Interests

Hematopathology - leukemia, lymphoma, and molecular genetics.

Research Interests

Mechanisms of Hox gene regulation by the mixed lineage leukemia protein, MLL, transcriptional deregulation by MLL fusion proteins, role of Hox genes in hematopoiesis and leukemia.

Brief Biography

Dr. Hess received a B.S. in Biophysics from Johns Hopkins University (1982), where he was co-valedictorian of his graduating class. In 1989, he received an M.D. and Ph.D. (Molecular Biology) from the Johns Hopkins University School of Medicine. After completing residency training in Anatomic Pathology at Brigham and Women's Hospital/Harvard Medical School (Boston), Dr. Hess completed fellowships in Hematopathology and Surgical Pathology at Brigham and Women's Hospital and Memorial Sloan-Kettering Cancer Center (New York).

He served as Assistant Professor of Pathology and Co-Director of the Hematopathology Training Program at Washington University School of Medicine and as assistant attending pathologist at Barnes-Jewish Hospital in St. Louis (1993-1999), where he worked closely with Dr. Stanley Kotsmeyer studying the molecular biology of leukemia. He joined the faculty of the Department of Pathology and Laboratory Medicine at the University of Pennsylvania Health System in 1999 as Associate Professor and was promoted to the rank of Professor in 2004. While at the University of Pennsylvania, Dr. Hess served as Director of Hematopathology and Co-Director of the Hematologic Malignancies Program at the Abramson Cancer Center.

Dr. Hess is a member of the College of American Pathologists, American Society of Hematopathologists, United States and Canadian Academy of Pathology, the American Society of Hematology, the American Association for Cancer Research and the American Association of Pathology Chairs. He serves as editor for a number of journals including the American Journal of Clinical Pathology and is board certified in Anatomic Pathology and Hematopathology.

Dr. Hess joined the faculty of the Department of Pathology at the University of Michigan in July 2005 as the Carl V. Weller Professor of Pathology and Chair.