Clinical Interests

Pathology, Interstitial Lung diseases, Pulmonary fibrosis, Adult respiratory distress syndrome (ARDS), Immunopathology

Research Interests

Lung injury and fibrosis, cytokines, myofibroblast biology and differentiation, smooth muscle actin gene expression, Pulmonary immunopathology
Research in this laboratory is directed at understanding the cellular and molecular mechanisms of tissue repair and fibrosis

Brief Biography

Academic Training: PhD Chemistry 1975 Indiana University; MD 1976 Indiana University

Residency Training: Anatomic Pathology 1976-1980 University of Connecticut Health Center; Board Certified 1979

Current Positions: Member, National Advissory Environmental Health Sciences Council, National Institute of Environmental health Sciences - National Institute of Health

Research Interests: Mechanisms of tissue/cell injury, repair and fibrosis; regulation of cytokine and collagen gene expression; chemokines and chemotactic recruitment of eosinophils and fibroblasts; myofibroblast role in fibrosis; regulation of alpha-smooth muscle actin gene expression and myofibroblast differentiation; myofibroblast apoptotic pathways in fibrosis; role of eosinophils in fibrosis.