Andrew G Muntean, PhD .

Email Address: andrewmu@med.umich.edu
Lab Phone: 734-615-1508
Mentor: Jay L Hess, MD, PhD.

Lab Address:
Pathology
2246 Med Sci I SPC 5602
1500 East Medical Center Drive
Ann Arbor, MI 48109-0938

Home State/Country: Indiana, USA

Research Interests: Transcription factor deregulation in leukemia


Granting University for Graduate Degree: The University of Chicago

1. Muntean AG, Hess JL. Epigenetic dysregulation in cancer. Am J Pathol. 2009 Oct;175(4):1353-61. Epub 2009 Aug 28. PubMed PMID: 19717641; PubMed Central PMCID: PMC2751531.
2. Muntean AG, Giannola D, Udager AM, Hess JL. The PHD fingers of MLL block MLL fusion protein-mediated transformation. Blood. 2008 Dec 1;112(12):4690-3. Epub 2008 Sep 16. PubMed PMID: 18796627; PubMed Central PMCID: PMC2597135.
3. Muntean AG, Hess JL. MLL-AF9 leukemia stem cells: hardwired or taking cues from the microenvironment? Cancer Cell. 2008 Jun;13(6):465-7. PubMed PMID: 18538728.
4. Huang Z, Richmond TD, Muntean AG, Barber DL, Weiss MJ, Crispino JD. STAT1 promotes megakaryopoiesis downstream of GATA-1 in mice. J Clin Invest. 2007 Dec;117(12):3890-9. PubMed PMID: 18060035; PubMed Central PMCID: PMC2096448.
5. Muntean AG, Pang L, Poncz M, Dowdy SF, Blobel GA, Crispino JD. Cyclin D-Cdk4 is regulated by GATA-1 and required for megakaryocyte growth and polyploidization. Blood. 2007 Jun 15;109(12):5199-207. Epub 2007 Feb 22. PubMed PMID: 17317855; PubMed Central PMCID: PMC1890844.
6. Muntean AG, Ge Y, Taub JW, Crispino JD. Transcription factor GATA-1 and Down syndrome leukemogenesis. Leuk Lymphoma. 2006 Jun;47(6):986-97. Review. PubMed
PMID: 16840187.
7. Muntean AG, Crispino JD. Differential requirements for the activation domain and FOG-interaction surface of GATA-1 in megakaryocyte gene expression and development. Blood. 2005 Aug 15;106(4):1223-31. Epub 2005 Apr 28. PubMed PMID: 15860665; PubMed Central PMCID: PMC1895209.
8. Mo FE, Muntean AG, Chen CC, Stolz DB, Watkins SC, Lau LF. CYR61 (CCN1) is essential for placental development and vascular integrity. Mol Cell Biol. 2002 Dec;22(24):8709-20. PubMed PMID: 12446788; PubMed Central PMCID: PMC139880.