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RESEARCH FACULTY Department of Pathology, University of Michigan
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	Ulysses G.J. Balis, M.D. Associate Professor Director, Clinical Informatics, Co-Director, Division of Pathology Informatics Numerical analysis and interpretation of digital histological (whole-slide) data sets in tandem with expression data and other high-order data, Vector Quantization (VQ) tools and Gallois Fields, design of support vector engines for automated region-of-interest based image repository query.

	Stephen W. Chensue, MD, PhD Associate Professor Cellular and molecular mechanisms of leukocyte mobilization during granulomatous inflammation.

	Arul M. Chinnaiyan, MD, PhD S.P. Hicks Collegiate Professor of Pathology Professor of Pathology and Urology Director of Pathology Microarray Center Director of the Tissue/Informatics Core of the UM Prostate S.P.O.R.E. Functional and clinical genomics; DNA and protein microarrays; bioinformatics; biomarkers; prostate and breast cancer; apoptosis.

	Kathleen R. Cho, MD Professor Molecular pathogenesis of gynecological tumors.

	Laura Cooling, MD Assistant Professor Role and regulation of globo-and lacto-family glycosyltransferases. LKE family and E. coli related diseases. Platelet glycoimmunology.

	Yali Dou, Ph.D. Assistant Professor Epigenetic mechanisms for transcription regulation and their implications in cancer development, stem cell self-renew and cell cycle regulation. Emphasis on histone methyltransferase and histone acetyltransferase complexes.

	Gregory R. Dressler, PhD Associate Professor Genetic basis of cellular differentiation and pattern formation in a complex multicellular tissue.

	Colin S. Duckett, PhD Associate Professor Regulation of apoptosis; control of cell survival by the tumor necrosis factor and transforming growth factor beta receptor superfamilies.

	Kojo Elenitoba-Johnson, MD Associate Professor and Director, Division of Translational Pathology Hematologic malignancies.

	Eric R. Fearon, MD, PhD Professor (Joint Appointment, Depts. Internal Medicine & Human Genetics) Tumor suppressor gene pathways in normal cell growth and differentiation, and the role of mutations in these pathways cancer.

	David O. Ferguson , MD, PhD Assistant Professor DNA Repair and Genomic Stability. We study the roles of DNA repair factors in preventing cancer and ensuring proper mammalian development. One of our focuses is on the Mre11/Rad50/NBS complex which is involved in inherited DNA repair deficiencies.

	Thomas J. Giordano, MD, PhD Associate Professor Global gene expression methods to classify human tumors, delineate novel diagnostic and predictive markers, and uncover genes involved in tumorigenesis.

	David Gordon, MD Professor of Pathology Assistant Dean for Diversity and Career Development Gene therapy for therapeutic angionesis

	Joel K. Greenson, MD Professor AIDS and the GI tract, infectious diseases of the liver and GI tract, and neoplasms of the GI tract and liver.

	Jay L. Hess, MD, PhD Carl V. Weller Professor and Chairman Mechanisms of Hox gene regulation by the mixed lineage leukemia protein MLL, transcriptional deregulation by MLL fusion proteins, role of Hox genes in hematopoiesis and leukemia

	Cory M. Hogaboam, PhD Asscociate Professor Chemokine contribution to chronic remodeling of the asthmatic airway in fungal asthma model.

	Naohiro Inohara, PhD Associate Research Scientist Study of proteins involved in mucosal immunity of the gastrointestinal tract, especially those involved in Crohn's disease.

	Kent J. Johnson, MD Professor Inflammation and oxygen radicals.

	Evan T. Keller, PhD Professor Basement membranes are specialized extracellular matrices which provide a substratum for cell attachment and thereby influence the differentiated phenotype of cells.

	Paul D. Killen, MD Associate Professor Basement membranes are specialized extracellular matrices which provide a substratum for cell attachment and thereby influence the differentiated phenotype of cells.

	Celina G. Kleer, MD Associate Professor Characterization of genes that drive highly aggressive breast cancer phenotypes. Identification and validation of tissue biomarkers that predict survival in patients with breast cancer using tissue microarrays.

	Steven L. Kunkel, PhD Senior Associate Dean for Research Co-Director, Division of General Pathology, Endowed Professor in Pathology Research Regulation of cytokine gene expression; macrophage pathobiology.

	Andrew P. Lieberman, MD, PhD Assistant Professor Inherited neurodegenerative diseases, with the goal of understanding the mechanisms underlying neurological dysfunction so as to develop effective treatments.

	Megan S. Lim, MD, PhD Associate Professor and Director, Hematopathology Hematologic malignancies.

	Peter C. Lucas, MD, PhD Assistant Professor Molecular Endocrinology; molecular mechanisms in the regulation of apoptosis and cancer development.

	Nicholas W. Lukacs, PhD Professor Cytokine/chemokine cascades associated with allergic airway responses (asthma) and T-lymphocyte-mediated pulmonary inflammation.

	Richard A. Miller, MD, PhD Professor Aging and T-cell activation; genetics of aging.

	Hedwig Murphy, MD, PhD Assistant Professor Endothelial cell responses in inflammation studied in cultured cells with emphasis on the enzyme source of endothelial cell oxidants, the role of endothelial cell derived oxidants in signaling and cell injury and the repertoire of endothelial cell derived cytokines and their role in inflammation.

	Alexey Nesvizhskii, PhD Assistant Professor Functional and clinical proteomics, bioinformatics, computational analysis of biological datasets, mass spectrometry data analysis.

	Gabriel Nuñez, MD Paul H. De Kruif Professor of Pathology Dr. Nuñez's laboratory is interested in signaling pathways regulating apoptosis and innate immunity and their role in the pathogenesis of inflammatory disease and cancer.

	Sem Phan, MD Professor Molecular and cellular mechanisms of tissue repair and fibrosis; regulation of extracellular matrix and cytokine gene expression; myofibroblast differentiation.

	Lloyd M Stoolman, MD Professor Lymphocyte recirculation and migration; functional characterization of the lymphocyte and endothelial receptors that mediate migration into lymphoid organs and sites of chronic inflammation; role of lymphocyte homing receptors in the hematogenous dissemination of lymphoid malignancies; role of lymphocyte-extracellular matrix interactions in lymphocyte migration.

	James Varani, PhD Professor Cell-substrate adhesion and cell motility in normal mammalian cells and their malignant counterparts; biosynthesis and surface expression of extracellular matrix molecules, such as fibronectin, laminin, and thrombospondin and their involvement as endogenous regulators of adhesion, motility, invasion, and metastasis.

	Peter A. Ward, MD Godfrey D. Stobbe Professor of Pathology Regulation of the inflammatory response, sepsis and signalling molecules involved in the inflammatory response.

	Jeffrey S. Warren, MD Aldred S. Warthin Professor Director, Division of Clinical Pathology Role of cellular redox status in modulating chemokine expression; pathogenesis of granulomatous vasculitis.

	Thomas Wilson, MD, PhD Associate Professor Normal functions of DNA double-strand break (DSB) repair pathways and the origins of chromosomal rearrangements associated with cancer, specifically translocations, deletions, and amplifications.

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