Laboratory:
Chemical Pathology
Referral Laboratory:
MiChart Code:
Bence Jones Protein, Random Urine
Soft Order Code:
BJS
Synonyms:
Immunoelectrophoresis (IEP), Urine Immunofixation (IFIX), Urine
Kappa Light Chains, Urine Lambda Light Chains, Urine
Light Chains, Urine Myeloma Proteins, Urine
Container:
Plastic urine container or BD yellow top urine tube
Normal Volume:
10 mL urine
Minimum Volume:
5 mL urine
Offsite Collection:
Collect first morning void urine specimen (preferred), preservative free. A 24 hour or random urine, preservative free, is also acceptable. Refrigerate up to 1 week.
Onsite Collection (Michigan Medicine Hospitals Only):
Urine. Preferred: first morning void urine specimen, preservative free. Other acceptable specimens: 24 hour urine, random urine (both preservative free).
Days Set Up:
Monday, Wednesday, Thursday
Analytic Time:
48 hours
Reference Range:
*Reference ranges may change over time. Please refer to the original patient report when evaluating results.
Negative for Bence Jones protein (no clonal free light chains identified). Pathologist interpretation of results provided.
Test Usage:
To detect clonal light chains. Useful in characterizing the species of protein in cases of proteinuria. Techniques can identify intact monoclonal protein and free light chains (Bence Jones protein). Of value in the study of monoclonal gammopathies and lymphoproliferative diseases, including lymphoma, multiple myeloma and Waldenstrom’s macroglobulinemia. Urine immunofixation is essential in amyloidosis or if a monoclonal band is present on urine protein electrophoresis.
Test Limitations:
Urine proteins are most concentrated in first am voided samples. Immunofixation is qualitative.
Test Methodology:
Immunofixation
Additional Information:
Test includes pathologist interpretation of results billed as a separate additional charge. This test is not available without interpretation.
LOINC:
55900-5
CPT Code:
86335
Fee Code:
21926
Pro Fee CPT:
86335-26
Pro Fee Code:
86335
Test ID:
153