Laboratory:
Sendout
Referral Laboratory:
Mayo FPDPG (Interscience)
Soft Order Code:
MMLR
Synonyms:
PG D2
Container:
Red top (preferred) or SST tube
Normal Volume:
3 mL serum
Minimum Volume:
1 mL serum
Offsite Collection:
Collect specimen in a red top (preferred) or SST tube. Centrifuge, aliquot serum or plasma into a plastic vial and freeze. Patient should not be on aspirin, indomethacin, or anti-inflammatory medications, if possible, for at least 48 hours prior to collection of specimen.
Onsite Collection (Michigan Medicine Hospitals Only):
Collect specimen in a red top or lavender top tube. Patient should not be on aspirin, indomethacin, or anti-inflammatory medications, if possible, for at least 48 hours prior to collection of specimen.
Days Set Up:
Monday - Friday
Analytic Time:
6-11 days
Reference Range:
*Reference ranges may change over time. Please refer to the original patient report when evaluating results.
35 - 115 pg/mL
Test Usage:
Prostaglandins are fatty acids derived from arachidonic acid metabolism. They are closely related to the Thromboxanes and Leukotrienes. Prostaglandin D2 is derived mainly from Prostaglandin H2, and is metabolized to Dihydroketo Prostaglandin D2. Prostaglandin D2 is excreted directly into the urine. The sites of highest Prostaglandin D2 activity are the brain, spinal cord, intestines, and stomach. Prostaglandin D2 is the major Prostaglandin produced by uterine tissue. Prostaglandin D2 is a potent bronchoconstrictor, neuromodulator, and anti-antithrombin agent. It also stimulates the secretion of Pancreatic Glucagon. Prostaglandin D2 has been found to have an anti-metastatic effect on many malignant tumor cells. Prostaglandin D2 production and circulating levels are drastically suppressed by aspirin and indomethacin.
Test Methodology:
EIA following extraction of specimens.
Additional Information:
Test sent to Mayo Medical Laboratories; performed by Interscience Institute.
LOINC:
12839-7
CPT Code:
84150
Template Code:
PROSTD2
Storage Temperature:
Frozen 60 days
Test ID:
4896