| Extractable Nuclear Antibodies SS-A and SS-B | |||||||||
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MiChart Code: Extractable Nuclear Antibodies, SS-A and SS-B
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Soft Order Code: SSAB2
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Synonyms:
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Container: SST tube
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Normal Volume: 0.5 mL serum
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Minimum Volume: 0.25 mL serum
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Offsite Collection: Collect specimen in SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate.
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Onsite Collection (Michigan Medicine Hospitals Only): Collect specimen in SST tube.
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Days Set Up: Monday - Friday
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Analytic Time: 1 day
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Reference Range: *Reference ranges may change over time. Please refer to the original patient report when evaluating results.
Negative
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Test Usage: SS-A (Ro) and SS-B (La) antibodies have a strong association with Sjogen’s syndrome and can be used to support the clinical diagnosis. SS-A is present in 70 - 75% and SS-B in 60 - 65% of patients with Sjogren’s syndrome. However, both SS-A and SS-B antibodies are present in SLE and other connective tissue disorders, so their presence must be interpreted in the clinical context. The BioPlex 2200 test system uses an affinity purified SS-A 60 antigen, a second SS-A 52 recombinant antigen, and an affinity purified SS-B antigen.
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Test Methodology: Multiplex Flow Immunoassay
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Additional Information: Panel includes SS-A (Ro) and SS-B (La) Antibodies. These antibodies may also be ordered individually.
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LOINC: 43100-7
CPT Code:86235 x2
Fee Code:20570 SSAB, 30930 SSB, 30931 SSA
Alternate Specimen:Red top tube.
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Test ID: 663
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