Laboratory:
Chemical Pathology
Referral Laboratory:
MiChart Code:
Protein Electrophoresis, Serum
Soft Order Code:
TPE
Synonyms:
Electrophoresis, Protein, Serum SPEP
Container:
SST tube
Normal Volume:
1 mL serum
Minimum Volume:
1.0 mL serum
Offsite Collection:
Collect specimen in SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate. If cryoglobulin is suspected, the specimen must be drawn in a red top tube and maintained at 37 degrees C.
Onsite Collection (Michigan Medicine Hospitals Only):
Collect specimen in an SST tube. If a cryoglobulin is suspected, the specimen must be drawn in a red top tube and maintained at 37 degrees C in a Thermos during transport to laboratory.
Days Set Up:
Monday - Friday
Analytic Time:
24 hours
Reference Range:
*Reference ranges may change over time. Please refer to the original patient report when evaluating results.
Total Protein (age >=12yrs): 6.0 - 8.3 g/dL; Albumin: 3.43 - 4.84 g/dL, Alpha-1 Globulin: 0.21 - 0.44 g/dL, Alpha-2 Globulin: 0.54 - 0.97 g/dL, Beta Globulin: 0.65 - 1.03 g/dL, Gamma Globulin: 0.70 - 1.47 g/dL, Albumin/Globulin Ratio: 0.88 - 2.30. Pathologist interpretation of results provided.
Test Usage:
Serum protein electrophoresis is an evaluation for monoclonal gammopathies, Waldenstrom's macroglobulinemia, multiple myeloma, liver disease, inflammatory states, nephrotic syndrome, amyloidosis and A1AT deficiency disease. Also used for evaluation for low back pain, arthritis, lymphoma, leukemia and anemia. The small bands and minor alterations detected will have different significance depending on the clinical situation.
Test Methodology:
Capillary Electrophoresis
Additional Information:
Test includes pathologist interpretation of results billed as a separate additional charge. This test is not available without interpretation. In order to provide accurate interpretation, abnormal results will be followed by serum immunoglobulins and serum immunofixation at an additional charge, and by immunoglobulin free light chains and/or immunoglobulin G subclass 4 at an additional charge, if clinically indicated. By ordering this test the clinician acknowledges that additional reflex testing will be performed and billed at a separate additional charge if indicated.
LOINC:
24351-9
CPT Code:
84165
Fee Code:
30951
Pro Fee CPT:
84165-26
Pro Fee Code:
84165
Alternate Specimen:
Red top tube.
Alternate Testing Site:
Body Fluids are not acceptable for this test at MLabs. Body Fluids may be sent for Mayo #8274. [3/99]
Test ID:
789