Pathology Conferences

5th Annual Protein Folding Diseases Initiative Symposium

By Catherine Bearman | 24 August

Oct. 11, 2018

The Knotty Problem of Protein Folding


8:30am - 4:30pm

A. Alfred Taubman Biomedical Science Research Building
Kahn Auditorium
The symposium will be highlighting the four research hubs with lectures by a member of each hub and a data blitz with junior faculty, senior postdoctoral fellows, and senior graduate students.

Our keynote speakers will be Lila Gierasch, PhD, Distinguished Professor and Chemistry and Biochemistry and Molecular Biology at University of Massachusetts Amherst, and Raymond J. Deshaies, PhD, Senior Vice President for Discovery Research at Amgen and a Visiting Associate at Caltech.  We will also feature a panel discussion.

This symposium will sell out. Reserve your spot now!  If you have any questions related to this event, please contact Cathy Niemiec at

Feel free to forward this information to members of your departments, especially to those faculty and students who receive such notices.


Symposium Program



Light Refreshments

Seminar Rooms A, B, C


Opening Remarks

by Henry Paulson, MD, PhD and Andrew P. Lieberman, MD, PhD
Lucile Groff Professor of Neurology, Director of the Michigan Alzheimer's Disease Center
and Gerald D. Abrams Collegiate Professor and Director of Neuropathology

Kahn Auditorium


Raymond J. Deshaies, PhD
Visiting Associate at the California Institute of Technology

P97/VCP: A Protein Unfoldase Whose Malfunction Causes Multi-System Proteinopathy

Kahn Auditorium


Michael Cianfrocco, PhD

Assistant Professor, Department of Biological Chemistry and Research Assistant Professor, U-M Life Sciences Institute

The Role of Intracellular Transport in Protein Folding Diseases

Kahn Auditorium


Brandon Ruotolo, PhD
Professor, Department of Chemistry

Gas-Phase Structural Biology: New Strategies for Assessing Protein Misfolding Targets

Kahn Auditorium


Break and Poster Review

Seminar Rooms A, B, C and Upper Atrium


Phyllis Hanson, MD, PhD
Gerty T. Cori Professor, Cell Biology and Physiology, Washington University, St. Louis

ESCRT Function in Endolysosomal Homeostasis

Kahn Auditorium


LUNCH and Poster Review

Seminar Rooms A, B, C, and Upper Atrium



Lila Gierasch, PhD
Distinguished Professor,  Department of Biochemistry and Molecular Biology, UMass Amherst

Hsp70 Chaperones: Versatile Molecular Machines that Facilitate Folding and More

Kahn Auditorium


Raymond J. Deshaies, PhD
Senior Vice President of Discovery Research at Amgen

Therapeutic Approaches to Protein Folding Disease Informed by Human Genetics

Kahn Auditorium

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Jang-Ho Cha, MD, PhD
Global Head Translational Medicine, Neuroscience, Novartis Institute for BioMedical Research

"Challenges & Opportunities in Neuroscience Drug Discovery"

Kahn Auditorium


Panel Discussion

Raymond Deshaies, PhD

Vince Groppi, PhD
Director, Center for the Discovery of New Medicines

Judith Heidebrink, MD
Associate Professor, Neurology

Kahn Auditorium


move this to 11:20 slot

Data Blitz

Amelia Glazier, BS

Amy Chang, PhD
Associate Professor, Molecular, Cellular, and Developmental Biology

Ryan Insolera, PhD
Postdoctoral Fellow, Molecular, Cellular, and Developmental Biology

Shannon Moore, PhD
Research Investigator, Molecular and Behavioral Neuroscience Institute

Kahn Auditorium


Closing Remarks and Poster Awards

Kahn Auditorium



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