Proteomics Resource Facility

Home Instrumentation Services Rates Submission Guidelines Forms Publications Bioinformatics Funding Opportunities Contact Information


Acknowledgment of Contributions

Publications containing data generated by the Proteomics Resource Facility (PRF) should include an acknowledgement of the PRF or include members as coauthors.  The PRF needs these acknowledgements and authorship to help demonstrate our contributions to the research community.  This in turn helps secure future funding to maintain a robust Core facility and provide professional development of its staff.  The Association of Biomolecular Resource Facilities (ABRF) has published a guideline to use when considering whether or not to include core laboratory members on publications.


  1. GATA-3 is a proto-oncogene in T-cell lymphoproliferative neoplasms.  Geng X, Wang C........Murga-Zamalloa C, Wilcox RA.  Blood Cancer J. 2022.  PMID: 36329027
  2. Sel1L-HRD1 ER-associated degradation suppresses hepatocyte hyperproliferation and liver cancer.  Bhattacharya A, Wei J, Song W, Gao B, Tian C, Wu SA, Wang J, Chen L, Fang D, Qi L.  iScience 2022:25(10).  PMID: 36238898
  3. Pak2-mediated phosphorylation promotes RORγt ubiquitination and inhibits colonic inflammation.  Kathania M, Kumar R, Lenou ET, Basrur V, Theiss AL, Chernoff J, Venuprasad K.  Cell Rep. 2022  40(11):111345. doi: 10.1016/j.celrep.2022.111345.  PMID: 36103814
  4. CGG repeats trigger translational frameshifts that generate aggregation-prone chimeric proteins.  Wright SE, Rodriguez CM, Monroe J, Xing J, Krans A, Flores BN, Barsur V, Ivanova MI, Koutmou KS, Barmada SJ, Todd PI.  Nucleic Acids Res. 2022, 50(15):8674-8689.  PMID: 35904811
  5. Discovery of a Highly Potent and Selective Dual PROTAC Degrader of CDK12 and CDK13.  Yang J, Chang Y, Tien JC, Wang Z, Zhou Y, Zhang P, Huang W, Vo J, Apel IJ, Wang C, Zeng VZ, Cheng Y, Li S, Wang GX, Chinnaiyan AM, Ding K.  J Med Chem. 2022 Aug 25;65(16):11066-11083. doi: 10.1021/acs.jmedchem.2c00384. Epub 2022 Aug 8.  PMID: 35938508
  6. Identification of secreted proteins by comparison of protein abundance in conditioned media and cell lysates.  Abbineni PS, Tang VT, da Veiga Leprevost F, Basrur V, Xiang J, Nesvizhskii AI, Ginsburg D.  Anal. Biochem. 2022.  PMID: 35973625
  7. EML2-S constitutes a new class of proteins that recognizes and regulates the dynamics of tyrosinated microtubules.  Hotta T, McAlear TS, Yue Y, Higaki T, Haynes SE, Nesvizhskii AI, Sept D, Verhey KJ, Bechstedt S, Ohi RCurr Biol. 2022 Aug 6:S0960-9822(22)01128-9.  PMID: 35963242
  8. Liver proteomic profile in mice on a high-far diet: Modulation with anti-tumor intervention.  Herber I, Zedan D, McClintock S, Varani J, Aslam MN.  FASEB J. 2022.  PMID: 35556832
  9. Sas20 is a highly flexible starch-binding protein in the Ruminococcus bromii cell-surface amylosome.  Cerqueira FM, Photenhauer AL, Doden HL, Brown AN, Abdel-Hamid AM, Morais S, Bayer EA, Wawrzak Z, Cann I, Ridlon JM, Hopikins J, Koropatkin NM.  J. Biol. Chem. 2022.  PMID: 35378131
  10. Mechanistic insights into consumption of the food additive zanthan gum by the human gut microbiota.  Ostrowski MP, La Rosa SL, Kunath BJ, Pereira G, Hagen LH, Varghese NJ, Qiu L, Yao T, Flint G, Li J, McDonald SP, Buttner D, Pudlo NA, Schnizlein MK, Young VB, Brumer H, Schmidt TM, Terrapon N, Lombard V, Henrissat B, Hamaker B, Eloe-Fadrosh EA, Tripathi A, Pope PB, Martens EC.  Nat. Microbiol. 2022.  PMID: 35365790
  11. Cell-matrix interactions contribute to barrier function in human colon organoids.  Varani J, McClintock SD, Aslam MN. Front. Med. (Lausanne), 2022.  PMID: 35360746
  12. RTL8 promotes nuclear localization of UBQLN2 to subnuclear compartments associated with protein quality control.  Mohan HM, Trzeciakiewicz H, Pithadia A, Crowley EV, Pacitto R, Safren N, Trotter B, Zhang C, Zhou X, Zhang Y, Basrur V. Paulson HL, Sharkey LM.  Cell Mol. Life Sci. 2022, 79(3):176.  PMID: 35247097
  13. Multiomic characterization of pancreatic cancer-associated macrophage polarization reveals deregulated metabolic programs driven by the GM-CSF-PI3K pathway.  Boyer S, Lee HJ, Steele N, Zhang L, Sajjakulnukit P, Andren A, Ward MH, Singh R, Basrur V, Zhang Y, Nesvizhskii AI, Pasca di Magliano M, Halbrook CJ, Lyssiotis CA. Elife. 2022 Feb 14;11:e73796. doi: 10.7554/eLife.73796.PMID: 35156921 
  14. Mechanistic convergence across initiation sites for RAN translation in fragile X associated tremor ataxia syndrome.  Zhang Y, Glineburg MR, Basrur V, Conlon K, Wright SE, Krans A, Hall DA, Todd PK.  Hum. Mol. Genet. 2022, PMID: 35137065
  15. A network of G-alpha-i signaling partners is revealed by proximity labeling proteomics analysis and includes PDZ-RhoGEF.  Chandan NR, Abraham S, SenGupta S, Parent CA, Smrcka AV.  Sci. Signal. 2022.  PMID: 35041463
  16. Targeting SWI/SNF ATPases in enhancer-addicted prostate cancer.  Xiao L, Parolia A, Qiao Y, Bawa P, Eyunni S, Mannan R, Carson SE, Chang Y, Wang X, Zhang Y, Vo JN, Kregel S, Simko SA, Delekta AD, Jaber M, Zheng H, Apel IJ, McMurry L, Su F, Wang R, Zelenka-Wang S, Sasmal S, Kare L, Mukherjee S, Abbineni C, Aithal K, Bhakta MS, Ghurye J, Cao X, Navone NM, Nesvizhskii AI, Mehra R, Vaishampayan U, Blanchette M, Wang Y, Samjdar S, Ramachandra M, Chinnaiyan M.  Nature 2021.  PMID: 34937944
  17. A validated analysis pipeline for mass spectrometry-based vitreous proteomics: New insights into proliferative diabetic retinopathy.  Weber SR, Zhao Y, Ma J, Gates C, da Veiga Leprevost F, Basrur V, Nesvizhskii AI, Gardner TW, Sundrstrom JM.  Clin. Proteomics 2021, 18(1):28.  PMID: 34861815
  18. Kinesin-binding protein remodels the kinesin motor to prevent microtubule binding.  Solon AL, Tan Z, Schutt KL, Jepsen L, Haynes SE, Nesvizhskii AI, Sept D, Stumpff J, Ohi R, Cianfrocco MS.  Sci. Adv. 2021.  PMID: 34797717
  19. Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas. Panwalkar P......Venneti S.  Sci. Transl. Med. 2021, 13(614):eabc0497.  PMID: 34613815
  20. SRSF protein kinase 1 modulates RAN translation and suppresses CGG repeat toxicity.  Malik I, Tseng YJ, Wright SE, Zheng K, Ramaiyer P, Green KM, Todd PK.  EMBO Mol. Med., 2021, 13(11):e14163.  PMID: 34542927
  21. Cryo-EM reveals new species-specific proteins and symmetry elements in the legionells pneumophila Dot/Icm T4SS.  Sheedlo MJ, Durie CL, Chung JM, Chang L, Roberts J, Swanson M, Lacy DB, Ohi MD.  Elife 2021.  PMID: 34519271
  22. Molecular determinants for alpha-tubulin methylation by SETD2.  Kearns S, Mason FM, Rathmell WK, Park IY, Walker C, Verhey KJ, Cianfrocco MA.  J. Biol. Chem. 2021, 297(1)100898.  PMID: 34157286
  23. Compound deletion of thrombosponding-1 and -2 results in a skeletal phenotype not predicted by the single gene knockouts.  Alford AI, Stephan C, Kozloff KM, Hankenson KD.  Bone, 2021.  PMID: 34425286
  24. Mechanism of mutant calreticulin-mediated activation of the thrombopoietin receptors in cancers.  Venkatesan A, Geng J, Kandarpa M, Wijeyesakere SJ, Bhide A, Talpaz M, Pogozheva ID, Raghavan M.  J. Cell Biol. 2021, 220(7)e20209179.  PMID: 33909030
  25. HIF-2a activation potentiates oxidative cell death in colorectal cancers by increasing cellular iron.  Singhal R, Mitta SR, Das NK, Kerk SA, Sajjakulnukit P, Solanki S, Andren A, Kumar R, Olive KP, Banerjee R, Lyssiotis CA, Shah YM.  J. Clin. Invest. 2021, 15:131(12)e143691.  PMID: 33914705
  26. SD-91 as a potent and selective STAT3 degrader capable of achieving complete and long-lasting tumor regression.  Zhou H, Bai L, Xu R, McEachern D, Chinnaswamy K, Li R, Wen B, Wang M, Yang CY, Meagher JL, Sun D, Stuckey JA, Wang S.  ACS Med. Chem Lett. 2021, 12(6):996-1004.  PMID: 34141084
  27. Proteomic analyses of vitreous in proliferative diabetic retinopathy: Prior studies and future outlook.  Weber SR, Zhao Y, Gates C, Ma J, da Veiga Leprevost F, Basrur V, Nesvizhskii AI, Garder TW, Sundstrom JM.  J. Clin. Med. 2021, 01(11):2309.  PMID: 34070658
  28. The antiviral enzyme viperin inhibits cholesterol biosynthesis.  Grunkemeyer TJ, Ghosh S, Patel AM, Sajja K, Windak J, Basrur V, Kim Y, Nesvizhskii AI, Kennedy RT, Marsh ENG.  J. Biol. Chem. 2021.  297(1):100824. PMID: 34029588
  29. Selective Inhibition of cullin 3 neddylation through covalent targeting of DCN1 protects mice from acetaminophen-induced liver toxicity.  Zhou H, Lu J, Chinnaswamy K, Stuckey JA, Liu L, McEachern D, Yand CY, Bernard D, Shen H, Rui L, Sun Y, Wang S.  Nat. Commun.  2021, 12(1):2621.  PMID: 33976147
  30. Spatially resolved cell polarity proteomics of a human epiblast model.  Wang S, Lin CW, Carleton AE, Cortex CL, Johnson C, Taniguchi LE, Sekulovski N, Townsend RF, Basrur V, Nesvizhskii AI, Zou P, Fu J, Gumucio DL, Duncan MC, Taniguchi K.  Sci. Adv. 2021, 7(17):eabd8407.  PMID: 33893097
  31. Mapping protein-protein interactions in homodimeric CYP102A1 by crosslinking and mass spectrometry.  Felker D, Zhang H, Bo Z, Lau M, Morishima Y, Scnell S, Osawa Y.  Biophys. Chem. 2021.  PMID: 33894563
  32. A Multi-mineral intervention to modulate colonic mucosal protein profile: Results from a 90-day trial in human subjects.  Aslam MN, McClintock SD, Jawad-Makki MAH, Knuver K, Ahmad HM, Basrur V, Bergin IL, Zick SM, Sen A, Turgeon DK, Varani J.  Nutrients, 2021, 13(3):939.  PMID: 33799486
  33. Discovery of a Napabucasin PROTAC as an effective degrader of the E3 ligase ZFP91.  Hanafi M, Chen X, Neamati N. J. Med. Chem. 2021, 64(3):1626-1648.  PMID: 33506674
  34. Parthenolide Destabilizes Microtubules by Covalently Modifying Tubulin. Hotta T, Haynes SE, Blasius TL, Gebbie M, Eberhardt EL, Sept D, Cianfrocco M, Verhey KJ, Nesvizhskii AI, Ohi R.  Curr Biol. 2021, 31(4):900-907.  PMID: 33482110
  35. Selenium-dependent metabolic reprogramming during inflammation and resolution.  Korwar AM, Hossain A, Lee TJ, Shay AE, Basrur V, Conlon K, Smith PB, Carlson BA, Salis HM, Patterson AD, Prabhu KS.  J. Biol. Chem. 2021.  PMID: 33581115
  36. ER-to-golgi transport and Sec23-dependent COPII vesicles regulate T cell allimmunity.  Kim S, Khoriaty R, Li L, McClune M, Kalfa TA, Wu J, Fujiwara H, Sun Y, Oravecz-Wilson K, King RA, Ginsburg D, Reddy P. J. Clin. Invest. 2021, 131(2)e136474.  PMID: 33463537
  37. A polycomb repressive complex is required for RNAi-mediated heterchromatin formation and dynamic distribution of nuclear bodies.  Xu J, Zhao X, Mao F, Basrur V, Ueberheide B, Chait BT, Allis CD, Taverna SD, Gao S, Wang W, Liu Y.  Nucleic Acids Res. 2021.  PMID:33412588
  38. DDB1 E3 ligase controls dietary fructose-induced ChREBPalpha stabilization and liver steatosis via CRY1.  Tong X, Zhang D, Shabandri O, Oh J, Jin E, Stamper K, Yang M, Zhao Z, Yin L.  Metabolism 2020.  107:154222.  PMID: 32246987
  39. Characterization of aminobenzylphenols as protein disulfide isomerase inhibitors in glioblastoma cell lines.  Shergalis A, Xue D, Gharbia FZ, Drinks H, Shrestha B, Tanweer A, Cromer K, Ljungman M, Neamati N. J. Med. Chem. 2020, 63(18):10263-10286.  PMID: 32830969
  40. Cryo-EM reveals species-specific components within the Helicobacter pylori Cag type IV secretion system core complex.  Sheedlow MJ, Chung JM, Sawhney N, Duries CL, Cover TL, Ohi MD, Lacy DB.  Elife. 2020. 9:e59495.  PMID: 32876048
  41. Deletion of Glutathione S-Transferase Omega 1 Activates Type I Interferon Genes and Downregulates Tissue Factor. Xu Y, Bankhead A 3rd, Tian X, Tang J, Ljungman M, Neamati N. Cancer Res. 2020,  80(17):3692-3705. PMID: 32571799
  42. Alveolar macrophage-derived extracellular vesicles inhibit endosomal fusion of influenza virus.Schneider DJ, Smith KA, Latuszek CE, Wilke CA, Lyons DM, Penke LR, Speth JM, Marthi M, Swanson JA, Moore BB, Lauring AS, Peters-Golden M. EMBO J. 2020, 39(16):e105057. PMID: 32643835
  43. Ulcertative colitis-derived colonoid culture: A multi-mineral-approach to improve barrier protein expression.  Aslam MN, McClintock SD, Addili D, Pandya S, Rehman H, Nadeem DM, Jawad-Makki MAH, Rizvi AH, Brenner MM, Dame MK, Turgeon DK, Varani J.  Front Cell Dev. Biol. 2020, 8:577221.  PMID: 33330453
  44. RACK1 mediates NLRP3 inflammasome activation by promoting NLRP3 active conformation and inflammasome assembly.  Duan Y, Zhang L, Angosto-Bazarra D, Pelegrin P, Nunez G, He Y. Cell Rep. 2020, 33(7):108405.  PMID: 33207200
  45. Integrated metabolic and epigenomic reprograming by H3K27M mutations in diffuse intrinsic Pontine gliomas.  Chung C, Sweha SR, Pratt D, Tamrazi B, Panwalkar P, Banda A, Bayliss J, Hawes D, Yang F, Lee HJ, Shan M, Cieslik M, Qin T, Wener CK, Wahl DR, Lyssiotis CA, Bian Z, Shotwell JB, Yadav VN, Koschmann C, Chinnaiyan AM, Bluml S, Judkins AR, Venneti S.  Cancer Cell, 2020, 38(3)334-349.  PMID: 32795401
  46. Calreticulin enhances the secretory trafficking of a misfolded alpha-1-antitrypsin.  Mohan HM, Yang B, Dean NA, Raghavan M.  J. Biol. Chem. 2020295(49):16754-16772.  PMID: 32978262
  47. Structural analysis of the Legionella pneumophila Dot/Icm type IV secretion system core complex.  Durie CL, Sheedlo MJ, Chung JM, Burne BG, Su M, Knight T, Swanson M, Lacy DB, Ohi MD.  Elife. 2020.  PMID: 32876045
  48. Low-dose Hsp90 inhibitor selectively radiosensitizes HNSCC and pancreatic xenografts.  Mehta RK, Pal S, Kondapi K, Sitto M, Dewar C, Devasia T, Schipper MJ, Thomas DG, Basrur V, Pai MP, Morishima Y, Osawa Y, Pratt WB, Lawrence TS, Nyati MK.  Clin. Cancer Res. 2020.  PMID: 32718999
  49. Ubiquitin ligase SMURF2 enhances epidermal growth factor receptor stability and tyrosine-kinase inhibitor resistance.  Ray P, Raghunathan K, Ahsan A, Allam US, Shukla S, Basrur V, Veatch S, Lawrence TS, Nyati MK, Ray D. J. Biol. Chem. 2020, 295(36):12661-12673.  PMID: 32669362
  50. Kir2.1 interactome mapping uncovers PKP4 as a modulator of the Kir2.1-regulated inward rectifier potassium currents.  Park SS, Ponce-Balbuena D, Kuick R, Guerrero-Serna G, Yoon J, Mellacheruvu D, Conlon KP, Basrur V, Nesvizhskii AI, Jalife J, Rual JF.  Mol. Cell Proteomics. 2020  PMID: 32541000
  51. Deubiquitination of NLRP6 inflammasome by Cyld critically regulates intestinal inflammation.  Mukherjee S, Kumar R, Tsakem Lenou E, Basrur V, Kontoyiannis DL, Ioakeimidis F, Mosialos G, Theiss AL, Flavell RA, Venuprasad K.  Nat. Immunol. 2020, 21(6):626-635.  PMID: 32424362
  52. Multicomponent microscale biosynthesis of unnatural cyanobacterial indole alkaloids.  Khatri Y, Hohlman RM, Mendoza J, Li S, Lowell AN, Asahara H, Sherman DH.  ACS Synth. Biol. 2020  PMID: 32302487
  53. TGFBR2 mediated phosphorylation of BUB1 at Ser-318 is required for transforming growth factor-b signaling.  Nyati S, Gregg BS, Xu J, Young G, Kimmel L, Nyati MK, Ray D, Speers C, Rehemtulla A. Neoplasia 2020, 22(4):163-178.  PMID: 32143140
  54. FBXW7 triggers degradation of KMT2D to favor growth of diffuse large B-cell lymphoma cells.  Saffie R, Zhou N, Rolland D, Onder O, Basrur V, Campbell S, Wellen KE, Elenitoba-Johnson KSJ, Capell BC, Busino L. Cancer Res. 2020,  21(6):626-635 PMID:32350066
  55. Multifaceted assessment of rituximab biosimilarity: The impact of glycan microheterogeneity on Fc function. Kang J, Kim SY, Vallejo D, Hageman TS, White DR, Benet A, Coghlan J, Sen KI, Ford M, Saveliev S, Tolbert TJ, Weis DD, Schwendeman SP, Routolo BT, Schwendeman A. Eur. J. Pharm. Biopharm. 2020, 146:114-124.  PMID: 31841688
  56. Quantitative proteomic landscape of metaplastic breast carcinoma pathological subtypes and their relationship to triple-negative tumors.  Djomehri SI, Gonzalez ME, da Veiga Leprevost F, Tekula SR, Chang HY, White MJ, Cimino-Mathews A, Burman B, Basrur V, Argani P, Nesvizhskii AI, Kleer CG.  Nat. Commun. 2020, 11(1):1723  PMID: 32265444
  57. Genetic predisposition for increased red blood cell distribution width is an early risk factor for cardiovascular and renal comorbidities. Cheng X, Mell B, Alimadadi A, Galla S, McCarthy CG, Chakraborty S, Basrur V, Joe B.  Dis. Model Mech. 2020  PMID: 32238420
  58. Androgen receptor degraders overcome common resistance mechanisms developed during prostate cancer treatment.  Kregel S, Wang C, Han X, Xiao L, Fernandez-Salas E, Bawa P, McCollum BL, Wilder-Romans K, Apel IJ, Cao X, Speers C, Wang S, Chinnaiyan AM.  Neoplasia 2020, 22(2)111-119. PMID: 31931431
  59. The GATOR2-mTORC2 axis mediates sestrin2-induced AKT ser/thr kinase activation. Kowalsky AH, Namkoong S, Mettetal E, Park H-W, Kazyken D, Fingar DC, Lee JH.  J. Biol. Chem. 2020  PMID: 31915252
  60. Cyclin-dependent kinase 4 inhibits the translational repressor 4E-BP1 to promote cap-dependent translation during mitosis-G1 transition.  Mitchell DC, Menon A, Garner AL.  FEBS Lett. 2019  PMID:31853978
  61. Structure-Based Design of Selective, Covalent G Protein-Coupled Receptor Kinase 5 Inhibitors.  Rowlands RA, Cato MC, Waldschmidt HV, Boulley RA, Chen Q, Avramova L, Larsen SD, Tesmer JJG, White AD.  ACS Med. Chem Lett. 2019, 10(12):1628-1634.  PMID: 31857838
  62. The RNA-binding protein SART3 promotes miR-34a biogenesis and G1 cell cycle arrest in lung cancer cells.  Sherman EJ, Mitchell DC, Garner AL. J. Biol. Chem. 2019, 294(46):17188-17196. PMID: 31619517
  63. The mechanism of cancer drug addiction in ALK-positive T-cell Lymphoma.  Rajan SS, Amin AD, Li L, Rolland DC, Li H, Kwon D, Kweh MF, Arumov A, Roberts ER, Yan A, Basrur V, Elenitoba-Johnson KSJ, Chen XS, Puvvada SD, Lussier YA, Bilbao D, Lim MS, Schatz JH. Oncogene, 2019.
  64. A neofunctionalized X-linked ampliconic gene family is essential for male fertility and equal sex ratio in mice.  Kruger AN, Brogley MS, Huizinga JL, Kidd JM, de Rooij DG, Hu YC, Mueller JL.  Curr. Biol. 2019, 29(21):3699-3706.
  65. A potent and selective small-molecule degrader of STAT3 achieves complete tumor regression in vivo.  Bail L, Zhou H, Xu R, Zhao Y, Chinnaswamy K, McEachem D, Chen J, Yang CY, Liu Z, Wang M, Liu L, Jiang H, Wen B, Kumar P, Meagher JL, Sun D, Stuckey JA, Wang S.  Cancer Cell 2019, 36(5):498-511. PMID:31715132
  66. Tumor-selective altered glycosylation and functional attenuation of CD73 in human hepatocellular carcinoma.  Alcedo KP, Guerrero A, Basrur V, Fu D, Richardson ML, McLane JS, Tsou CC, Nesvizhskii AI, Welling TH, Lebrilla CB, Otey CA, Kim HJ, Omary MB, Snider NT.  Hepatol. Commun. 2019, 3(10):1400-1414. PMID: 31592495
  67. Multi-omics profiling reveals key signaling pathways in ovarian cancer controlled by STAT3.  Lu T, Bankhead A III, Ljungman M, Neamati N.  Theranostics 2019, 9(19):5478-5496. PMID:31534498
  68. Calcium-induced differentiation in normal human colonoid cultures: cell-cell/cell-matrix adhesion, barrier formation and tissue integrity.  Attili D, McClintock SD, Rizvi AH, Pandya S, Rehman H, Nadeem DM, Richter A, Thomas D, Dame MK, Turgeon DK, Varani J, Aslam MN.  PLoS One 2019, 14(4)e0215122 PMID: 30995271
  69. Functional and Mechanistic interrogation of BET bromodomain degraders for the treatment of metastatic castration-resistant prostate cancer.  Kregel S, Malik R, Asangani IA, Wilder-Romans K, Rajendiran T, Xiao L, Vo JN, Soni T, Cieslik M, Fernandez-Salas E, Zhou B, Cao X, Speers C, Wang S, Chinnaiyan AM.  Clin. Cancer Res. 2019, 25(13):4038-4048. PMID:30918020
  70. Chemoproteomic profiling uncovers CDK4-mediated phosphorylation of the translational suppressor 4E-BP1.  Mitchell DC, Menon A, Garner AL.  Cell Chem. Biol. 2019, 26(7):980-990. PMID: 31056462
  71. Oxygen and conformation dependent protein oxidation and aggregation by porphyrins in hepatocytes and light-exposed cells.  Maitra D, Carter EL, Richardson R, Rittie L, Basrur V, Zhang H, Nesvizhskii AI, Osawa Y, Worlf MW, Ragsdale SW, Lehnert N, Hermann H, Omary MB.  Cell Mol. Gastroenterol. Hepatol. 2019. PMID:31173894
  72. Constitutive release of CPS1 in bile and its role as a protective cytokine during acute liver injury.  Park MJ, D'Alecy LG, Anderson MA, Basrur V, Feng Y, Brady GF, Kim DI, Wu J, Nesvizhskii AI, Lahann J, Lukacs NW, Fontana RJ, Omary MB.  Proc. Natl. Acad. Sci. USA, 2019, 116(18):9125-9134. PMID: 30979808
  73. Co-expression analysis reveals mechanisms underlying the varied roles of NOTCH1 in NSCLC.  Sinicropi-Yao SL, Amann JM, Lopez DLY, Cerciello F, Coombes KR, Carbone DP.  J. Thorac. Oncol. 2019, 12(2):223-236.  PMID: 30408569
  74. Seleniproteome identification in inflamed murine primary bone marrow-derived macrophages by nano-LC Orbitrap Fusion Tribrid mass spectrometry. Korwar AM, Shay AE, Basrur V, Conlon K, Prabhu KS.  J. Am. Soc. Mass Spectrom. 2019, 30(7):1276-1283.
  75. Therapeutic lifestyle changes improve HDL function by inhibiting myeloperoxidase-mediated oxidation in patients with metabolic syndrome.  Matthew AV, Li L, Byun J, Guo Y, Michailidis G, Jaiswal M, Chen YE, Pop-Busui R, Pennathur S.  Diabetes Care, 2018, 41(11):2431-2437
  76. Design, Synthesis, and Biological Evaluation of Novel Allosteric Protein Disulfide Isomerase Inhibitors.  Yang S, Shergalis A, Lu D, Kyani A, Lu Z, Ljungman M, Neamati N. J. Med. Chem. 2019, 62(7):3447-3474.
  77. The full-length cytochrome P450 enzyme CYP102A1 dimerizes at its reductase domains and has flexible heme domains for efficient catalysis.  Zhang H, Yokom AL, Cheng S, Su M, Hollenberg PF, Southworth DR, Osawa Y.  J. Biol. Chem. 2018, 293(20):7727-7736.
  78. Temporal profiling establishes a dynamic S-palmitoylation cycle.  Won SJ, Martin BR.  ACS Chem. Biol. 2018, 13(6):1560-1568
  79. BAP1 regulation of the key adaptor protein NCoR1 is critical for g-globin gene repression.  Yu L, Jearawiriyapaisarn N, Lee MP, Hosoya T, Wu Q, Myers G, Lim KC, Kurita R, Nakamura Y, Vojtek AB, Rual JF, Engel JD.  Genes Dev. 2018, 32(23-24):1537-1549
  80. SUMOylation of ROR-gt inhibits IL-17 expression and inflammation via HDAC2.  Singh AK, Khare P, Obaid A, Conlon KP, Basrur V, DePinho RA, Venuprasad K. Nat. Commun. 2018, 9(1):4515
  81. Abnormal RNA stability in amyotrophic lateral sclerosis.  Tank EM, Figueroa-Romero C, Hinder LM, Bedi K, Archbold HC, Li X, Weskamp K, Safren N, Paez-Colasante X, Pacut C, Thumma S, Paulsen MT, Guo K, Hur J, Ljungman M, Feldman EL, Barmada SJ.  Nat. Commun. 2018, 9(1):2845
  82. p38-mediated phosphorylation at T367 induces EZH2 cytoplasmic localization to promote breast cancer metastasis.  Anwar T, Arellano-Garcia C, Ropa J, Chen YC, Kim HS, Yoon E, Grigsby S, Basrur V, Nesvizhskii AI, Muntean A, Gonzalez ME, Kidwell KM, Nikolovska-Coleska Z, Kleer CG. Nat. Commun. 2018, 9(1):2801
  83. HSC70 is a chaperone for wild-type and mutant cardiac myosin binding protein C.  Glazier AA, Hafeez N, Mellacheruvu D, Basrur V, Nesvizhskii AI, Lee LM, Shao H, Tang V, Yob JM, Gestwicki JE, Helms AS, Day SM.  JCI Insight 2018, 3(11).
  84. PAF1 complex interactions with SETDB1 mediate promoter H3K9 methylation and transcriptional repression of Hoxa9 and Meis1 in acute myeloid leukemia.  Ropa J, Saha N, Chen Z, Serio J, Chen W, Mellacheruvu D, Zhao L, Basrur V, Nesvizhskii AI, Muntean AG. Oncotarget 2018, 9(31):22123-22136
  85. Lipotoxicity induces hepatic protein inclusions through TANK binding kinase 1-mediated p62/sequestosome 1 phosphorylation.  Cho CS, Park HW, Ho A, Semple IA, Kim B, Jang I, Park H, Reilly S, Saltiel AR, Lee JH.  Hepatology 2018, 68(4):1331-1346.  PMID: 29251796
  86. Calcium-induced differentiation of human colon adenomas in colonoid culture: Calcium alone versus calcium with additional trace elements.  McClintock SD, Colacino JA, Attili D, Dame MK, Richter A, Reddy A, Basrur V, Rizvi AH, Turgeon DK, Varani J, Aslam MN.  Cancer Prev. Res (Phila) 2018, 11(7):413-428.
  87. A metabolic function of FGFR3-TACC3 gene fusions in cancer.  Frattini V, Pagnotta SM, Tala, Fan JJ, Russo MV, Lee SB, Garofano L, Zhang J, Shi P, Lewis G, Sanson H, Frederck V, Castano AM, Cerulo L, Rolland DCM, Mall R, Mokhtari K, Elenitoba-Johnson KSJ, Sanson M, Huang X, Ceccarelli M, Lasorella A, Iavarone A. Nature 2018, 553(7687):222-227.
  88. Myeloperoxidase mediated HDL oxidation and HDL proteome changes do not contribute to dysfunctional HDL in Chinese subjects with coronary artery disease.  Wang G, Mathew AV, Yu H, Li L, He L, Gao W, Liu X, Gua Y, Byun J, Zhang J, Chen YE, Pennathur S.  PLos One 2018, 13(3):e0193782.
  89. A novel reporter for real-time, quantitative imaging of AKT-directed K63-poly-ubiquitination in living cells.  Nyati S, Chaudhry N, Chatur A, Gregg BS, Kimmel L, Khare D, Basrur V, Ray D, Rehemtulla A.  Oncotarget 2018, 9(13):11083-11099.
  90. The Ewing sarcoma secretome and its response to activation of Wnt/beta-catenin signaling.  Hawkins AG, Basrur V, da Veiga Leprevost F, Pedersen E, Sperring C, Nesvizhskii AI, Lawlor ER.  Mol. Cell Proteomics 2018, 17(5):901-912.
  91. IL-17-driven intestinal fibrosis is inhibited by Itch-mediated ubiquitination of HIC-5.  Paul J, Singh AK, Kathania M, Elviche TL, Zeng M, Basrur V, Theiss AL, Venuprasak K.  Mucosal. Immunol. 2018, 11(2):427-436
  92. A comparative global phosphoproteomic analysis of obinutuzumab (GA101) versus rituximab (RTX) against RTX sensitive and resistant Burkitt lymphoma (BL) demonstrates differential phosphorylation of signaling pathway proteins after treatment.  Awasthi A, Rolland DCM, Ayello J, van de Ven C, Basrur V, Conlon K, Fermin D, Barth MJ, Klein C, Elenitoba-Johnson KSJ, Lim MS, Cairo MS.  Oncotarget 2017, 8(69):113895-113909.
  93. Qunatitative proteomics identifies STEAP4 as a critical regulator or mitochondrial dysfunction linking inflammation and colon cancer.  Xue x, Bredell BX, Anderson ER, Martin A, Mays C, Nagao-Kitamoto H, Huang S, Gyorffy B, Greenson JK, Hardiman K, Spence JR, Kamada N, Shah YM.  Proc. Natl. Acad. Sci. USA, 2017, 114(45)E9608-E9617.

  94. RBPJ/CBF1 interacts with L3MBTL3/MBT1 to promote repression of Notch signaling via histone demthylase KDM1A/LSD1.  Xu T, Park SS, Giaimo BD, Hall D, Ferrante F, Ho DM, Hori K, Anhezini L, Ertl I, Bartkuhn M, Zhang H, Milon E, Ha K, Conlon KP, Kuick R, Govindarajoo B, Zhang Y, Sun Y, Dou Y, Basrur V, Elenitoba-Johnson KS, Nesvizhskii AI, Ceron J, Lee CY, Borggrefe T, Kovall RA, Rual JF.  EMBO J. 2017, 36(21):3232-3249.

  95. Nuclear lamina genetic variants, including a truncated LAP2, in twins and siblings with nonalcoholic fatty liver disease.  Brady GF, Kwan R, Ulintz PJ, Nguyen P, Bassirian S, Basrur V, Nesvizhskii AI, Loomba R, Omary MB.  Hepatology 2017, 67(5):3232-3249.

  96. Involvement of p38-bTrCP-Tristetraprolin-TNFa axis in radiation pneumonitis.  Krishnamurthy PM, Shukla S, Ray P, Mehra R, Nyati MK, Lawrence TS, Ray D.  Oncotarget, 2017, 8(29):47767-79.

  97. Functional proteogenomics reveals biomarkers and therapeutic targets in lymphomas.  Rolland DCM, Basrur V, Jeon YK, McNeil-Schwalm C, Fermin D, Conlon KP, Zhou Y, Nq SY, Tsou CC, Brown NA, Thomas DG, Bailey NG, Omenn GS, Nesvizhskii AI, Root DE, Weinstock DM, Faryabi RB, Lim MS, Elenitoba-johnson KSJ.  Proc. Natl. Acad. Sci. USA 2017, 114(25):6581-6586.

  98. Protein aggregation with poly(vinyl) alcohol surfactant reduces double emulsion-encapsulated mammalian cell-free expression.  Ho KK, Lee JW, Durand G, Majumder S, Liu AP.  PLoS One 2017, 12(3):e0174689. 

  99. Pyrimidine tract-binding protein 1 mediates pyruvate kinase M2-dependent phosphorylation of signal transducer and activator of transcription 3 and oncognesis in anaplastic large cell lymphoma.  Hwang SR, Murga-Zamalloa C, Brown N, Basappa J, McDonnell SR, Mendoza-Reinoso V, Basrur V, Wilcox R, Elenitoba-Johnson K, Lim MS. Lab. Invest. 2017, 97(8):962-970.

  100. IL-22 controls iron-dependent nutritional immunity against sytemic bacterial infections.  Sakamoto K, Kim YF, Hara H, Kamada N, Caballero-Flores G, Tolosano E, Soares MP, Puente JL, Inohara N, Nunez G.  Sci. Immunol. 2017

  101. Targeted Degradation of BET proteins in triple-negative breast cancer.  Bai L, Zhou B, Yang CY, Ji J, McEachern D, Przybranowski S, Jiang H, Hu J, Xu F, Zhao Y, Liu L, Fernandez-Salas E, Zu J, Doy Y, Wen B, Sun D, Meagher JL, Stuckey J, Hayes DF, Li S, Ellis MJ, Wang S.  Cancer Res. 2017, 77(9):2476-2487.

  102. NPM-ALK phosphorylates WASP Y102 and contributes to oncogenesis of anaplastic large cell lymphoma.  Murga-Zamalloa CA, Mendoza-Reinoso v, Sahasrabuddhe AA, Rolland D, Hwang SR, McDonnell SR, Sciallis AP, Wilcox RA, Basrur V, Elenitoba-Johnson K, Lim MS.  Oncogene, 2017, 36(15):2085-2094.

  103. EMC1-dependent stabilization drives membrane penetration of a partially destabilized non-enveloped virus.  Bagchi P, Inoue T, Tsai B.  Elife 2016.

  104. Iron uptake via DMT1 integrates cell cycle with JAK-STAT3 signaling to promote colorectal tumorigenesis.  Xue X, Ramakrishnan SK, Weisz K, Triner D, Xie L, Attili D, Pant A, Gyorffy B, Zhan M, Carter-Su C, Hardiman KM, Wang TD, Dame MK, Varani J, Brenner D, Fearon ER, Shah YM.  Cell Metab. 2016, 24(3):447-61.

  105. NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux.  He Y, Zeng MY, Yang D, Motro B, Nunez G.  Nature, 2016, 530(7590):354-7.

  106. Loss of the ubiquitin-conjugating enzyme Ube2W results in susceptibility to early postnatal lethality and defects in skin, immune and male reproductive systems.  Wang B, Merillat SA, Vincent M, Huber AK, Basrur V, Mangelberger D, Zeng L, Elenitoba-Johnson K, Miller RA, Irani DN, Dlugosz AA, Schnell S, Scaglione KM, Paulson HL.  J. Biol. Chem. 2016, 291(6):3030-42.

  107. Aberrant expression of napsin A in a subset of malignant lymphomas.  Nam SJ, Kim S, Kim JE, Lim MS, Elenitoba-Johnson KS, Kim CW, Jeon YK.  Histol. Histopathol. 2016, 31(2):213-21.

  108. Ndfip1 regulates itch ligase activity and airway inflammation via UbcH7.  Kathania M, Zeng M, Yadav VN, Moghaddam SJ, Yang B, Venuprasad K.  J. Immunol. 2015, 194(5):2160-7.

  109. Pharmacoproteomics identifies combinatorial therapy targets for diffuse large B cell lymphoma.  Goldstein RL, Yang SN, Taldone T, Chang B, Gerecitano J, Elenitoba-Johnson K, Shaknovich R, Tam W, Leonard JP, Chiosis G, Cerchietti L, Melnick A.  J. Clin. Invest. 2015, 125(12):4559-71.

  110. The PIAS-like coactivator Zmiz1 is a direct and selective cofactor of Notch1 in T cell development and leukemia.  Pinnel N, Yan R, Cho HJ, Keeley T, Murai MJ, Liu Y, Alarcon AS, Qin J, Wang Q, Kuick R, Elenitoba-Johnson KS, Maillard I, Samuelson LC, Cierpicki T, Chiang MY.  Immunity 2015, 43(5):870-83.

  111. Tumor-selective proteotoxicity of verteporfin inhibits colon cancer progression independently of YAP1.  Zhang H, Ramakrishnan SK, Triner D, Centofanti B, Maitra D, Gyorffy B, Sebolt-Leopold JS, Dame MK, Varani J, Brenner DE, Fearon ER, Omary MB, Shah YM.  Sci. Signal. 2015, 8(397):ra98

  112. Ambient light promotes selective subcellular proteotoxicity after endogenous and exogenous porphyrinogenic stress.  Maitra D, Elenbaas JS, Whitesall SE, Basrur V, D'Alecy LG, Omary MB.  J. Biol. Chem. 2015, 290(39):23711-24

  113. The E3 ubiquitin ligase Itch inhibits p38alpha signaling and skin inflammation through the ubiquitylation of Tab1.  Theivanthiran B, Kathania M, Zeng M, Anguiano E, Basrur V, Vanderfriff T, Pascual V, Wei WZ, Massoumi R, Venuprasad K.  Sci. Signal. 2015, 8(365):ra22

  114. Conversion of the LIMA1 tumour suppressor into an oncogenic LMO-like protein by API2-MALT1 in MALT lymphoma.  Nie Z, Du MQ, McAllister-Lucas LM, Lucas PC, Bailey NG, Hogaboam CM, Lim MS, Elenitoba-Johnson KS.  Nat. Commun. 2015, 6:5908

  115. Differential proteomic analysis of endemic and sporadic Epstein-Barr virus-positive and negative Burkitt lymphoma.  El-Mallawany NK, Day N, Ayello J, Van de Ven C, Conlon K, Fermin D, Basrur V, Elenitoba-Johnson K, Lim M, Cairo MS.  Eur. J. Cancer 2015, 51(1):92-100

  116. Intrinsic disorder drives N-terminal ubiquitination by Ube2W.  Vittal V, Shi L, Wenzel DM, Scaglione KM, Duncan ED, Basrur V, Elenitoba-Johnson KS, Baker D, Paulson HL, Brzovic PS, Klevit RE.  Nat. Chem. Biol. 2015, 11(1):83-89

  117. Fbxo45 inhibits calcium-sensitive proteolysis of N-cadherin and promotes neuronal differentiation.  Chung FZ, Sahasrabuddhe AA, Ma K, Chen X, Basrur V, Lim MS, Elenitoba-Johnson KS.  J. Biol. Chem. 2014, 289(41):28448-59

  118. TRIP13 promotes error-prone nonhomologous end joining and induces chemoresistance in head and neck cancer. Banerjee R, Russo N, Liu M, Basrur V, Bellile E, Palanisamy N, Scanlon CS, van Tubergen E, Inglehart RC, Metwally T, Mani RS, Yocum A, Nyati MK, Castilho RM, Varambally S, Chinnaiyan AM, D'Silva NJ. Nat. Commun. 2014, 5:4527.

  119. Fbxo45-mediated degradation of the tumor-suppressor Par-4 regulates cancer cell survival. Chen X, Sahasrabuddhe AA, Szankasi P, Chung F, Basrur V, Rangnekar VM, Pagano M, Lim MS, Elenitoba-Johnson KS. Cell Death Differ. 2014, 21(10):1535-45.

  120. 3,4-methylenedioxy-β-nitrostyrene inhibits NLRP3 inflammasome activation by blocking assembly of the inflammasome. He Y, Varadarajan S, Munoz-Planillo R, Burberry A, Nakamura Y, Nunez G.  J. Biol. Chem. 2014, 289(2):1142-50.

  121. Global phosphoproteomic profiling reveals distinct signatures in B-cell non-hodgkin lymphomas. Rolland D, Basrur V, Conlon K, Wolfe T, Fermin D, Nesvizhskii AI, Lim MS, Elenitoba-Johnson KS. Am. J. Pathol. 2014, 184(5):1331-42.

  122. KRAS protein stability is regulated through SMURF2:UBCH5 complex-mediated b-TrCP1 degradation. Shukla S, Allam US, Ahsan A, Chen G, Krishnamurthy PM, Marsh K, Rumschlag M, Shankar S, Whitehead C, Schipper M, Basrur V, Sourthworth DR, Chinnaiyan AM, Rehemtulla A, Beer DG, Lawrence TS, Nyati MK, Ray D Neoplasia 2014, 16(2):115.

  123. Distraction-induced intestinal growth:  The role of mechanotransduction mechanisms in a mouse model of short bowel syndrome.  Sueyoshi R, Woods Ignatoski KM, Okawada M, Teitelbaum DH.  Tissue Eng. Part A. 2014, 20(3-4):830-41

  124. Involvement of ractive oxygen species in a feed-forward mechanisms of Na/K-ATPase-mediated signaling transduction.  Yan Y, Shapiro AP, Haller S, Katragadda V, Liu L, Tian J, Basrur V, Malhotra D, Xie ZJ, Abraham NG, Shapiro JI, Liu J.  J. Biol. Chem. 2013, 288(47):34249-58.

  125. Staphylococcus d-toxin induces allergic skin disease by activating mast cells.  Nakamura Y, Oscherwitz J, Cease KB, Chan SM, Munoz-Planillo R, Hasegawa M, Villaruz AE, Cheung GY, McGavin MJ, Travers JB, Otto M, Inohara N, Nunez G. Nature 2013, 503(7476):397-401.

  126. Probing the mechanism of cyanobacterial aldehyde decarbonylase using a cyclopropyl aldehyde.  Paul B, Das D, Ellington B, Marsh EN. J. Am. Chem. Soc. 2013, 135(14):5234-7

  127. Inflammation produces catecholamine resistance in obesity via activation of PDE3B by the protein kinases IKKe and TBK1.  Mower J, Uhm M, Reilly SM, Simon J, Leto D, Chiang SH, Chang L, Saltiel AR. eLife 2013, 2:e01119.

  128. Fusion peptides from oncogenic chimeric proteins as specific biomarkers of cancer.  Conlon KP, Basrur V, Rolland D, Wolfe T, Nesvizhskii AI, Maccoss MJ, Lim MS, Elenitoba-Johnson KS.  Mol. Cell Proteomics 2013, 12(10):2714-23.

  129. Integrated phosphoproteomic and metabolomics profiling reveals NPM-ALK-mediated phosphorylation of PKM2 and metabolic reprogramming in anaplastic large cell lymphoma.  McDonnell RPS, Hwang SR, Rolland D, Murga-Zamalloa C, Basrur v, Conlon KP, Fermin D, Wolfe T, Rasking A, Ruan C, Jiang J-K, Thomas CJ, Hogaboam CM, Burant CF, Elenitoba-Johnson KSJ, Lim MS.  Blood 2013, 122(6): 959-68.

  130. Saccharomyces cerevisiae DNA ligase IV supports imprecise end joining independently of its catalytic activity.  Chiruvella KK, Liang Z, Birkeland SR, Basrur V, Wilson TE.  PLOS Genetics. 2013,9(6):e1003599.

  131. The ubiquitin conjugating enzyme (E2) Ube2w ubiquitinates the N-terminus of substrates. Scaglione KM, Basrur V, Ashraf NS, Konen JR, Elenitoba-Johnson KS, Todi SV, Paulson HL. J Biol Chem. 2013, 288(26):18784-8

  132. CGG repeat-associated translation mediates neurodegeneration in fragile X tremor ataxia syndrome.  Todd PK, Oh SY, Krans A, He F, Sellier C, Frazer M, Renoux AJ, Chen KC, Scaglione KM, Basrur V, Elenitoba-Johnson K, Vonsattel JP, Louis ED, Sutton MA, Taylor JP, Mills RE, Charlet-Berguerand N, Paulson HL.  Neuron. 2013, 78(3):440-55.

  133. RNF111-dependent neddylation activates DNA damage-induced ubiquitination.  Ma T, Chen Y, Zhang F, Yang CY, Wang S, Yu X.  Mol Cell. 201349(5):897-907.

  134. Citrullinated calreticulin potentiates rheumatoid arthritis shared epitope signaling.  Ling S, Cline EN, Hauq TS, Fox DA, Holoshitz J.  Arthritis Reheum. 2013, 65(3):618-25.

  135. MMSET stimulates myeloma cell growth through microRNA-mediated modulation of c-MYC.  Min DJ, Ezponda T, Kim MK, Will CM, Martinez-Garcia E, Popovic R, Basrur V, Elenitoba-Johnson KS, Licht JD. Leukemia. 2013, 27(3):686-94. doi: 10.1038/leu.2012.269.

  136. Cysteine reactivity distinguishes redox sensing by the heat-inducible and constitutive forms of heat shock protein 70. Miyata Y, Rauch JN, Jinwal UK, Thompson AD, Srinivasan S, Dickey CA, Gestwicki JE. Chem Biol. 2012, 19(11):1391-9.

  137. Analysis of the tau-associated proteome reveals that exchange of Hsp70 for Hsp90 is involved in tau degradation. Thompson AD, Scaglione KM, Prensner J, Gillies AT, Chinnaiyan A, Paulson HL, Jinwal UK, Dickey CA, Gestwicki JE.  ACS Chem Biol. 2012, 7(10):1677-86.

  138. Fbxw7α- and GSK3-mediated degradation of p100 is a pro-survival mechanism in multiple myeloma.  Busino L, Millman SE, Scotto L, Kyratsous CA, Basrur V, O'Connor O, Hoffmann A, Elenitoba-Johnson KS, Pagano M.  Nat Cell Biol. 2012,14(4):375-85.

  139. ECSASB2 mediates MLL degration during hematopoietic differentiation.  Wang J, Muntean AG, Hess JL.  Blood. 2012,119(5):1151-61. 

  140. Site specific interaction of the polyphenol EGCG with the SEVI amyloid precursor peptide PAP(248-286).  Popovych N, Brender JR, Soong R, Vivekanandan S, Hartman K, Basrur V, Macdonald PM, Ramamoorthy A.  J Phys Chem B. 2012, 116(11):3650-8. 

  141. An N-glycosylation analysis of human alpha-2-macroglobulin using an integrated approach.  Lin Z, Lo A, Simeone DM, Ruffin MT, Lubman DM.  J Proteomics Bioinform. 2012, 5:127-34.

  142. NPM-ALK signals through glycogen synthase kinase 3β to promote oncogenesis.  McDonnell SR, Hwang SR, Basrur V, Conlon KP, Fermin D, Wey E, Murga-Zamalloa C, Zeng Z, Zu Y, Elenitoba-Johnson KS, Lim MS.  Oncogene. 2012, 31(32):3733-40.

  143. Identification and characterization of Hoxa9 binding sites in hematopoietic cells. Huang Y, Sitwala K, Bronstein J, Sanders D, Dandekar M, Collins C, Robertson G, MacDonald J, Cezard T, Bilenky M, Thissen N, Zhao Y, Zeng T, Hirst M, Hero A, Jones S, Hess JL.  Blood, 2012, 119(2):388

  144. Urine glycoprotein profile reveals novel markers for chronic kidney disease.  Vivekanandan-Giri A, Slocum JL, Buller CL, Basrur V, Ju W, Pop-Busui R, Lubman DM, Kretzler M, Pennathur S.  Int J Proteomics. 2011, 2011:214715.

  145. Ordered assembly of heat shock proteins, Hsp26, Hsp70, Hsp90, and Hsp104, on expanded polyglutamine fragments revealed by chemical probes.  Walter GM, Smith MC, Wisén S, Basrur V, Elenitoba-Johnson KS, Duennwald ML, Kumar A, Gestwicki JE.  J Biol Chem. 2011, 286(47):40486-93.

  146. Function of leukemogenic mixed lineage leukemia 1 (MLL) fusion proteins through distinct partner protein complexes.  Biswas D, Milne TA, Basrur V, Kim J, Elenitoba-Johnson KS, Allis CD, Roeder RG.Proc Natl Acad Sci U S A. 2011,108(38):15751-6.

  147. Mechanistic rationale for inhibition of poly(ADP-ribose) polymerase in ETS gene fusion-positive prostate cancer.  Brenner JC, Ateeq B, Li Y, Yocum AK, Cao Q, Asangani IA, Patel S, Wang X, Liang H, Yu J, Palanisamy N, Siddiqui J, Yan W, Cao X, Mehra R, Sabolch A, Basrur V, Lonigro RJ, Yang J, Tomlins SA, Maher CA, Elenitoba-Johnson KS, Hussain M, Navone NM, Pienta KJ, Varambally S, Feng FY, Chinnaiyan AM.  Cancer Cell. 2011,19(5):664-78.

  148. Abacus: a computational tool for extracting and pre-processing spectral count data for label-free quantitative proteomic analysis.  Fermin D, Basrur V, Yocum AK, Nesvizhskii AI.  Proteomics. 2011, 11(7):1340-5.

  149. MLL-AF9 and MLL-ENL alter the dynamic association of transcriptional regulators with genes critical for leukemia.  Monroe SC, Jo SY, Sanders DS, Basrur V, Elenitoba-Johnson KS, Slany RK, Hess JL.  Exp Hematol. 2011, 39(1):77-86.

  150. An Ash2L/RbBP5 heterodimer stimulates the MLL1 methyltransferase activity through coordinated substrate interactions with the MLL1 SET domain.  Cao F, Chen Y, Cierpicki T, Liu Y, Basrur V, Lei M, Dou Y.  PLoS One. 2010, 5(11):e14102

  151. Activity and cellular functions of the deubiquitinating enzyme and polyglutamine disease protein ataxin-3 are regulated by ubiquitination at lysine 117.  Todi SV, Scaglione KM, Blount JR, Basrur V, Conlon KP, Pastore A, Elenitoba-Johnson K, Paulson HL.  J Biol Chem2010, 285(50):39303-13.

  152. A bimolecular affinity purification method under denaturing conditions for rapid isolation of a ubiquitinated protein for mass spectrometry analysis.  Maine GN, Li H, Zaidi IW, Basrur V, Elenitoba-Johnson KS, Burstein E.  Nat Protoc. 2010, 5(8):1447-59.

  153. The PAF complex synergizes with MLL fusion proteins at HOX loci to promote leukemogenesis.  Muntean AG, Tan J, Sitwala K, Huang Y, Bronstein J, Connelly JA, Basrur V, Elenitoba-Johnson KS, Hess JL.  Cancer Cell. 2010, 17(6):609-21.

  154. Multiple interactions recruit MLL1 and MLL1 fusion proteins to the HOXA9 locus in leukemogenesis.  Milne TA, Kim J, Wang GG, Stadler SC, Basrur V, Whitcomb SJ, Wang Z, Ruthenburg AJ, Elenitoba-Johnson KS, Roeder RG, Allis CD.  Mol Cell. 2010, 38(6):853-63.

  155. Regulation of the copper chaperone CCS by XIAP-mediated ubiquitination.  Brady GF, Galbán S, Liu X, Basrur V, Gitlin JD, Elenitoba-Johnson KS, Wilson TE, Duckett CS.  Mol Cell Biol. 2010, 30(8):1923-36.

  156. KDM2A represses transcription of centromeric satellite repeats and maintains the heterochromatic state.  Frescas D, Guardavaccaro D, Kuchay SM, Kato H, Poleshko A, Basrur V, Elenitoba-Johnson KS, Katz RA, Pagano M.  Cell Cycle. 2008, 7(22):3539-47.