The PRF is equipped with two Thermo Scientific mass spectrometers devoted exclusively for proteomic analysis. These include:
Orbitrap Fusion Tribrid with ETD
Q Exactive HF
Note: Both mass spectrometers are equipped with dedicated RSLC-nano (Dionex) UHPLCs and nanospray sources.
Orbitrap Tribrid Fusion with ETD: (Acquired with funding from the Protein Folding DIsorder Initiative, a part of University of Michigan's Strategic Research Initiative).
The Thermo Scientific™ Orbitrap Fusion™ Tribrid™ mass spectrometer combines the best of quadrupole, Orbitrap, and ion trap mass analysis in a revolutionary Tribrid architecture that delivers unprecedented depth of analysis. It enables life scientists analyzing even the most challenging low-abundance, high-complexity, or difficult samples to identify more compounds more quickly, quantify more accurately, and elucidate structures more thoroughly. The instrument can perform parallel CID, HCD, ETD, EThcD and ETciD fragmentation analysis to provide the most in depth information about the complex samples.
Inside Pathology is an newsletter published by the Chairman's Office to bring news and updates from inside the department's research and to become familiar with those leading it. It is our hope that those who read it will enjoy hearing about those new and familiar, and perhaps help in furthering our research.
Collaborates between Wayne County and the Department of Pathology and Social Work at U-M are imporving the lives of patient families and the faculty and staff who serve them, becoming a model for the future.
Director of Autopsy and Forensic Services, Dr. Jeffrey Jentzen, reflects on his career, beginning with his training in Minneapolis in the early ‘80 and including high profile cases such as the Jeffrey Dahmer serial killings.
In December, 2015, the Board of Regents approved the design for the Clinical Pathology Laboratories Relocation and Renovation project. Senior Project Manager, Christine Baker, explains how Lean Facility Design is being used to involve faculty and staff in creating the plans for their new workspace.
Expertise in Reference Laboratory Services
MLabs, established in 1985, functions as a portal to provide pathologists, hospitals. and other reference laboratories access to the faculty, staff and laboratories of the University of Michigan Health System’s Department of Pathology. MLabs is a recognized leader for advanced molecular diagnostic testing, helpful consultants and exceptional customer service.