Publications
See also Google Scholar.
Manuscripts Under Review

Spatially resolved multi-omic profiling of human hippocampus reveals region-specific alterations in major depressive disorder
(Cell, Under Review)
Xiao Y*, Su G*, Tan Y*, Asaad N, Deng Y, Li T, Lu Y, Kim D, Rosoklija GB, Enninful A, Bai Z, Liu Y, Sissoko C, Mariani M, Wu T, Nguyen P, Liang H, Santiago A, Dwork AJ, Hen R, Nolan GP, Mann JJ, Ma S, Leong KW, Boldrini M, Fan R.
SPACEc: A Streamlined, Interactive Python Workflow for Multiplexed Image Processing and Analysis
BioRxiv
Tan Y*, Kempchen TN*, Becker M, Haist M, Feyaerts D, Xiao Y, Su G, Rech AJ, Fan R, Hickey JW, Nolan GP, https://doi.org/10.1101/2024.06.29.601349 (2024) (Nature Communications, Accepted).
Antidepressants promote developmental-like plasticity through remodeling of extracellular matrix
BioRxiv
Nguyen PT, Tamura S, Sun E, Shi Y, Xiao Y, Lacefield C, Turi G, Hen R. https://doi.org/10.1101/2025.01.03.631260 (2025). (Science, Under Review).
Mapping morphological malformation to genetic dysfunction in blood vessel organoids with 22q11. 2 Deletion Syndrome.
BioRxiv
He S, Xu C, Lao HS, Chauhan S, Xiao Y, Willner MJ, Jin Y, McElroy S, Rao SB, Gogos JA, Tomer R, Azizi E, Xu B, Leong KW., https://doi.org/10.1101/2021.11.17.468969 (2021).
Publications
*Technology Innovation: spatial sequencing of the non-coding RNAs
*Highlighted in Cell in the front cover
*Technology innovation: Spatial co-sequencing of mRNA and open chromatin platform
*Highlighted in Nature Research Briefing
Gene expression and epigenetic regulation co-mapped in brain tissues. Nature, Advance online publication. https://www.nature.com/articles/d41586-023-00436-z (2023).
*Highlighted in Nature Reviews Genetics Research Highlight
Layering epigenomic and transcriptomic space. Nature Reviews Genetics, Advance online publication. https://www.nature.com/articles/s41576-023-00596-8 (2023).
*Highlighted in Blood Editorial Commentary
Shelter from the cytokine storm in myelofibrosis. Blood, 141 (20): 2415–2416 (2023). https://www.sciencedirect.com/science/article/pii/S0006497123005633
*Highlighted in Nature Nanotechnology Research Briefing
Targeting and reducing abdominal fat using polycations. Nature Nanotechnology 17(12):1249-1250 (2022).
*Highlighted in Cell Stem Cell Editorial Preview
Craft A and Galloway J. Specialized cells for building tissue bridges. Cell Stem Cell, 29(12):1615-1616 (2022).
*Technology innovation: Spatial ATAC-seq Platform for Detection of Open Chromatin
*Featured in Nature Structural & Molecular Biology Research Highlight
Chromatin found in space, Perdigoto C. Nature Structural & Molecular Biology, 29 (843) (2022).
*Technology innovation: Spatial mRNA-seq Platform
*Highlighted in Nature Methods
*Selected as Inside Front Cover
*Selected as Inside Front Cover
*Selected as Inside Back Cover
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