Hematopathology Section

Lauren B. Smith, MD, Section Director

The Hematopathology (HP) Section consists of a diverse group of hematopathologists with varied interests. All of the hematopathologists provide diagnostic evaluation of tissue and fluids for both University of Michigan patients and clients through the MLabs program.  The interpretive reports include the integration of tissue morphology and ancillary testing such as flow cytometric analysis, molecular diagnostic testing and cytogenetic results. Our hematopathologists typically review over 4,900 tissue cases and over 2,000 fluid and peripheral smears yearly.

Many members of the HP section carry out research activities in Hematopathology. Areas of interest include:  Acute myeloid leukemias, Epigenetics of Myelodysplastic Syndromes, Hodgkin and non-Hodgkin lymphomas.  The faculty consistently produce manuscripts and present at national and international conferences. Other interests include the development and implementation of integrated Hematopathology virtual case review tool.

In addition to the surgical tissue evaluations the Section is comprised of multiple laboratories including Hematology, Flow Cytometry, Coagulation, the Bone Marrow Lab and Urinalysis.

  •  The Hematology Lab is staffed with highly qualified medical technicians and technologists, many of whom have several years of experience. The Lab offers high volume automated testing, differential counting of peripheral blood smears and body fluids as well as specialized assays.
  • The Flow Cytometry Laboratory provides full range of services on peripheral blood, fluids and tissues including evaluations for leukemias, lymphomas, and Paroxysmal Nocturnal Hemoglobinuria and Immunodeficiency states.  State-of-the-art, 10-color assays are currently in use in the Flow Laboratory. 
  • The Coagulation Lab provides both routine coagulation assays as well as many special coagulation tests with interpretive evaluations. 
  •  In addition to the processing of the bone marrow specimens, the Bone Marrow Lab provides a unique service in which the technologists attend most bone marrow procedures and assist in the procedure to ensure the highest quality of specimen to be reviewed by the hematopathologists. 
  •  Our urinalysis area is primarily automated employing the use of the Iris for both chemical and microscopic evaluation of urine samples.

The Hematopathology Fellowship Program is an ACGME approved one year fellowship program.

The University of Michigan hematopathologists are actively involved with the Hematology/Oncology and Radiology Departments in collaborative multidisciplinary patient care conferences.

For more information, please call 734-936-1874.