Pathology News

New Breast Cancer Metastasis Mechanism Uncovered

By Celina Kleer | 31 January

The laboratory of Dr. Celina Kleer, Harold A. Oberman Collegiate Professor, isolated human mesenchymal stem cells from breast cancer metastasis. The lab discovered that a collagen receptor tyrosine kinase, DDR2, mediates stromal-cancer communication and induces breast cancer metastasis. The study provides the basis for the development of DDR2 inhibitors. The article appeared in Cell Reports and can be found at www.cell.com.

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