University of Michigan Pathology faculty Douglas Fullen, MD, May Chan, MD, Aleodor Andea, MD, along with David Arps, MD, from Consolidated Pathology Consultants (a former dermatopathology fellow at University of Michigan), have co-authored a new book titled, Handbook of Direct Immunofluorescence: A Pattern-Based Approach to Skin and Mucosal Biopsies.
The book is a guide for practicing general pathologists, dermatopathologists, and oral and ophthalmic pathologists who interpret biopsies from patients with blistering and inflammatory disorders requiring direct immunofluorescence examination. It also serves as a resource for clinicians who care for patients with these disorders and trainees who are studying in the field.
The book consists of an introductory section that describes immunofluorescence techniques and protocols, followed by 29 chapters covering the range of conditions which the pathologist is likely to encounter upon direct immunofluorescence examination. The book uses a pattern-based approach which provides a logical framework for learning about these disorders. It is the only book published in the past decade dedicated to this subject, and includes the most up-to-date information on newly described disease entities. Each chapter succinctly describes the clinical presentation, pathogenesis, histopathology, direct immunofluorescence and, when appropriate, indirect immunofluorescence and enzyme-linked immunosorbent assays for the specific disorders. Nonspecific direct immunofluorescence findings and diagnostic pitfalls are also discussed.