Opportunities exist for cutting-edge research projects in the areas of health and disease associated with cross talk between immune cells, microbes and the intestinal barrier. State of the art approaches using molecular biochemistry, knockout mouse models under normal and germ free conditions, cell lines, purified leukocytes and ex-vivo organoids generated from stem cells are being employed to investigate fundamental mechanisms regulating mucosal barrier function, leukocyte trafficking, cell proliferation, migration and wound repair in the gastrointestinal tract. Our studies have recently resulted in new patent applications and high impact, translationally relevant publications.
Successful candidates will become part of a highly productive and collaborative team of junior and senior investigators in a modern, interconnected laboratory space. Within the group, there is a strong commitment to mentorship and an excellent track record of success for both academic and industrial career track oriented individuals.
Candidates must possess a Ph.D. or M.D./Ph.D., preference will be given to individuals with expertise in molecular/cell biology, protein biochemistry of eukaryotic systems and mucosal immunology. Proficiency in English and strong communication skills are necessary. Interested individuals should send CV/resume and contact information for 2-3 references to Drs. Asma Nusrat and Charles Parkos, University of Michigan, E-mail: anusrat [at] umich.edu, cparkos [at] umich.edu.
We are actively recruiting research technicians to become integral members of our group studying fundamental mechanisms regulating mucosal barrier function, leukocyte trafficking, cell proliferation, migration and wound repair in the gut. The successful candidate will have the opportunity to perform experiments using a variety of state of the art techniques involving cell biology, protein biochemistry, molecular biology, and in-vivo animal models. This position offers unique opportunities for ambitious individuals to interact with a diverse group including other technicians, graduate students, post-docs and faculty. We are looking for an enthusiastic individual with a Bachelor’s degree in biological science or equivalent. Previous laboratory experience, proficiency in English, strong work ethic, computer (word processing, power point and spreadsheet software) and communication skills as well as the ability to work efficiently in a team setting are required. Responsibilities will include assisting with experiments using tissue culture of epithelial cell lines, transfection, western blotting, QPCR/PCR, transformation of bacteria, DNA/RNA isolation, cDNA synthesis, frozen sectioning and H&E staining, maintaining databases, experimental records and laboratory inventories. Additional responsibilities include assistance with ongoing experiments and in-vivo mouse work to analyze mucosal barrier function and wound repair. Please inquire by sending a CV/resume and cover letter to Dr. Monique O’Leary, University of Michigan, E-mail: moniqueo [at] umich.edu.
We accept rotation students interested in working on cutting-edge research projects related to understanding mechanisms regulating mucosal barrier function, leukocyte trafficking, cell proliferation, migration and wound repair in the gastrointestinal tract. Please inquire by sending a CV/resume to Drs. Asma Nusrat and Charles Parkos, University of Michigan, E-mail: anusrat [at] umich.edu, cparkos [at] umich.edu.
Undergraduates who are interested in exploring exciting research projects focused on investigating the mechanisms that modulate intestinal barrier during healthy and pathologic inflammatory states please send a CV/resume and cover letter to Dr. Monique O’Leary, University of Michigan, E-mail: moniqueo [at] umich.edu. Selected applicants will assist in research experiments and be trained in essential lab techniques including PCR/QPCR, DNA/RNA/protein isolation, western blotting, cell culture, and immunofluorescence. Excellent communication and organization skills as well as a strong work ethic are required. The ideal candidates will be expected to develop a good rapport with the members of the lab. No prior experience is required, and all majors are welcome.