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Sunita Shankar, M.S.

Lab Address:

5411 Cancer Center
1500 E. Medical Center Dr.
Ann Arbor, MI 48109-0938

 

  

Undergraduate Institution:

  • B.S.: Microbiology, Mumbai, India
  • M.S.: Biotechnology, Tamil Nadu, India

 

Research interests : Cancer Biology

Publications:

  • Xiao-Song Wang*, Sunita Shankar*, Saravana M. Dhanasekaran*, Bushra Ateeq, Atsuo T. Sasaki, Xiaojun Jing, Daniel Robinson, Qi Cao, John R. Prensner, Anastasia K. Yocum, Rui Wang, Daniel F. Fries, Bo Han, Irfan A. Asangani, Xuhong Cao, Yong Li, Gilbert S. Omenn, Dorothee Pflueger, Anuradha Gopalan, Victor E. Reuter, Emily Rose Kahoud, Lewis C. Cantley, Mark A. Rubin, Nallasivam Palanisamy, Sooryanarayana Varambally, and Arul M. Chinnaiyan. Characterization of KRAS Rearrangements in Metastatic Prostate Cancer. Cancer Discov. 2011 Jun 1;1(1):35-43
  • Dan R Robinson, Shanker Kalyana-Sundaram,Yi-Mi Wu, Sunita Shankar, Xuhong Cao, Bushra Ateeq, Irfan A Asangani, Matthew Iyer, Christopher A Maher, Catherine S Grasso, Robert J Lonigro, Michael Quist, Javed Siddiqui, Rohit Mehra, Xiaojun Jing, Thomas J Giordano, Michael S Sabel, Celina G Kleer, Nallasivam Palanisamy, Rachael Natrajan, Maryou B Lambros, Jorge S Reis-Filho, Chandan Kumar-Sinha, & Arul M Chinnaiyan. Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer. Nature Medicine. 2011 Nov 20;17(12):1646-51
  • Jung H. Kim, Saravana M. Dhanasekaran, John R. Prensner, Xuhong Cao, Daniel Robinson, Shanker Kalyana-Sundaram, Christina Huang, Sunita Shankar, Xiaojun Jing, Matthew Iyer, Ming Hu, Lee Sam, Catherine Grasso, Christopher A. Maher, Nallasivam Palanisamy, Rohit Mehra, Hal D. Kominsky, Javed Siddiqui, Jindan Yu, Zhaohui S. Qin and Arul M. Chinnaiyan Deep sequencing reveals distinct patterns of DNA methylation in prostate cancer. Genome Research. 2011 Jul;21(7):1028-41.
  • Rohit Mehra*, Chandan Kumar-Sinha*, Sunita Shankar*, Robert J. Lonigro, Xiaojun Jing, Neena E. Philips, Javed Siddiqui, Bo Han, Xuhong Cao, David C. Smith, Rajal B. Shah, Arul M. Chinnaiyan, and Kenneth J. Pienta. Characterization of Bone Metastases from Rapid Autopsies of Prostate Cancer Patients. Clinical Cancer Research. 2011 Jun 15;17(12):3924-32
  • Nallasivam Palanisamy, Bushra Ateeq, Shanker Kalyana-Sundaram, Dorothee Pflueger, Kalpana Ramnarayanan, Sunita Shankar, Bo Han, Qi Cao, Xuhong Cao, Khalid Suleman, Chandan Kumar-Sinha, Saravana M Dhanasekaran, Ying-bei Chen, Raquel Esgueva, Samprit Banerjee, Christopher J LaFargue, Javed Siddiqui, Francesca Demichelis, Peter Moeller, Tarek A Bismar, Rainer Kuefer, Douglas R Fullen, Timothy M Johnson, Joel K Greenson, Thomas J Giordano, Patrick Tan, Scott A Tomlins, Sooryanarayana Varambally, Mark A Rubin, Christopher A Maher & Arul M Chinnaiyan. Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma. Nature Medicine Vol. 16(7) July 2010. Pages 793-798
  • Jindan Yu, Jianjun Yu, Ram-Shankar Mani, Qi Cao, Chad J. Brenner, Xuhong Cao, Xiaoju Wang, Longtao Wu, James Li, Ming Hu, Yusong Gong, Hong Cheng, Bharathi Laxman, Adaikkalam Vellaichamy, Sunita Shankar, Yong Li, Saravana M. Dhanasekaran, Roger Morey, Terrence Barrette, Robert J. Lonigro, Scott A. Tomlins, Sooryanarayana Varambally, Zhaohui S. Qin, and Arul M. Chinnaiyan. An Integrated Network of Androgen Receptor, Polycomb, and TMPRSS2-ERG Gene Fusions in Prostate Cancer Progression. Cancer Cell 17, 443–454, May 18, 2010
  • Sooryanarayana Varambally, Qi Cao,Ram-Shankar Mani, Sunita Shankar, Xiaosong Wang, Bushra Ateeq, Bharathi Laxman, Xuhong Cao, Xiaojun Jing, Kalpana Ramnarayanan, J. Chad Brenner, Jindan Yu, Jung H. Kim, Bo Han, Patrick Tan, Chandan Kumar-Sinha, Robert J. Lonigro, Nallasivam Palanisamy, Christopher A. Maher, and Arul M. Chinnaiyan. Genomic Loss of microRNA-101 Leads to Overexpression of Histone Methyltransferase EZH2 in Cancer. Science. 2008 Dec 12;322(5908):1695-9
  • Bo Han, Rohit Mehra, Saravana M. Dhanasekaran, Jindan Yu, Anjana Menon, Robert J. Lonigro, Xiaosong Wang, Yusong Gong, Lei Wang, Sunita Shankar, Bharathi Laxman, Rajal B. Shah, Sooryanarayana Varambally, Nallasivam Palanisamy, Scott A. Tomlins, Chandan Kumar-Sinha, and Arul M. Chinnaiyan. A fluorescence in situ hybridization screen for E26 transformation-specific aberrations: identification of DDX5-ETV4 fusion protein in prostate cancer. Cancer Research. 2008 Sep15;68(18):7629-37.
  • Sunita Shankar-Sinha*, Gabriel A. Valencia*, Brian K. Janes, Jessica K. Rosenberg, Chris Whitfield, Robert A. Bender, Ted J. Standiford and John G. Younger. Klebsiella pneumoniae O-antigen contributes to Bacteremia and Lethality in a Murine Model of Pneumonia. Infection Immunity. 2004 Mar; 72(3):1423-30.
  • John G. Younger, Sunita Shankar-Sinha, Marc Mickiewicz, Adam S. Brinkman, Gabriel A. Valencia, J. Vidya Sarma, Ellen M. Younkin, Theodore J. Standiford, Firas S. Zetoune and Peter A. Ward. Murine Complement Interactions with Pseudomonas aeruginosa and their Consequences during Pneumonia. American Journal Respiratory Cell and Molecular Biology. 2003, 29: 432-438.
  • Arul M. Chinnaiyan, Markus Huber-Lang, Chandan Kumar-Sinha, Terrence R. Barrette, Sunita Shankar-Sinha, Vidya J. Sarma, Vaishalee A. Padgaonkar, Peter A. Ward.> Molecular signatures of sepsis: multiorgan gene expression profiles of systemic inflammation. American Journal Pathology. 2001 Oct; 159(4): 1199-209.
  • Arul M. Chinnaiyan, Uttara Prasad, Sunita Shankar, Daniel A. Hamstra, Murthy Shanaiah, Thomas L. Chenevert, Brian D. Ross, and Alnawaz Rehemtulla. Combined effect of tumor necrosis factor-related apoptosis-inducing ligand and ionizing radiation in breast cancer therapy. Proceedings National Academy of Sciences USA. 2000 Feb 15; 97(4): 1754-9.
     
Patent:
(WO/2009/150491) INTERFERON EPSILON (IFNE1) AS A MARKER FOR TARGETED CANCER THERAPY.
Inventors: SHANKAR, Sunita; (US)., VED, Urvi; (US)., SHARMA, Somesh; (IN).