The Celina Kleer lab at the University of Michigan Department of Pathology and Rogel Cancer Center has found a new mechanism that fuels metastasis in triple negative breast cancers. In their new study they show that EZH2, a master regulator of cell type identity, known to function through methylation of histones, has a new, unexpected function in aggressive breast cancers. By adding methyl groups to the p38 protein, EZH2 enhances the ability of breast cancer cells to spread to other tissue throughout the body, a process known as metastasis.This work increases our understanding of how triple negative breast cancer cells spread based on the cooperation between EZH2 and p38 and may lead to more effective ways to block metastasis [...]
This summer, Michigan Medicine officially welcomed 23 new Fellows and Clinical Instructors into the Department of Pathology.
Drs. Laura Lamps, Maria Westerhoff, and Angela Wu become the three newest Assistant Chairs in the Department of Pathology with a focus on Wellness, Staff Development and Diversity, Equity and Inclusion [...]
Patients with relapsed multiple myeloma are resistant to commonly used treatments. Researchers are one step closer to understanding the genetic reason why.
Learn more about Scott Marquette's recent visit to the Clinical Microbiology laboratory and about the Visual Inventory Management pilot, a new initiative that is intended to help lab staff better organize their tools, resources and assets within the lab setting [...]
Congratulations to Kristina Martin, Clinical Pathology Operations Director, who recently took home the award for the Scientific-Assembly Laboratory Administration award from the American Society for Clinical Laboratory Science (ASCLS) [...]
Effective July 1, 2022, Dr. Sriram Venneti, Professor of Pathology, was appointed as Scientific Research Director and Dr. Carl Koschmann, Assistant Professor of Pediatrics, was appointed as Clinical Research Director for the Chad Carr Pediatric Brain Tumor Center (CC-PBTC).
We recognize Dr. Jolanta Grembecka on being named the inaugural Richard and Susan Rogel Professor of Cancer Therapeutics. An induction ceremony will be held later this year. Please join us in congratulating her on this honor!
A landmark study into quantitative image analysis in ER, PgR, and HER2 in invasive breast carcinoma was recently published in the American Journal of Clinical Pathology. Dr. Mustafa Yousif, Assistant Professor of Breast Pathology and Informatics, and colleagues conducted a retrospective study of 1,367 invasive breast carcinomas of all histopathology subtypes, for which ER, PgR, and HER2 were analyzed by manual scoring [...]
On Saturday, May 21, 2022, Michigan Medicine hosted its first-ever Youth Summit at Michigan Stadium in Ann Arbor. The event, which included local middle schools from Ann Arbor, Ypsilanti, and surrounding communities, invited young students out to the Big House in order to come and experience a day in medicine. The Department of Pathology had a station set up on the concourse, where these students could come try out microscopy, learn about urinalysis and practice phlebotomy on a fake arm [...]
As part of the ongoing series of renovations of the clinical laboratories at University Hospital, the Blood Bank Laboratory — and its landmark front window — will relocate about 135 feet to the east on Sunday, June 5. A wayfinding graphic can be found here.
The International Society of Gynecological Pathologists has posted a podcast featuring discussion with Dr. Stephanie Skala about the use of p53/CK17 immunohistochemistry in the diagnosis of differentiated vulvar intraepithelial neoplasia. The podcast highlights the recent publication by former trainees Drs. Emily McMullen-Tabry, Shula Schechter, and Grace Wang, former UM faculty Dr. Andrew P Sciallis, and current UM faculty Drs. Steven Hrycaj, May Chan, and Stephanie Skala [...]
The Department of Pathology is pleased to welcome Andrew Szczembara as our new Point of Care (POC) Manager. A 2010 UM graduate, Szczembara joined the department in March 2012 as an inpatient phlebotomist on the midnight shift. He later transitioned to Brighton Health Center as a Phlebotomist Specialist lead [...]
On May 11, the Department of Pathology recognized the Class of 2022 Medical Laboratory Science (MLS) interns, who successfully completed the program. A graduation ceremony was held at the Superior Conference room, hosted by Allied Education Health Program Manager Karen Barron, MT (ASCP). The event featured remarks from Drs. Jeffrey Myers, Kathleen Cho, and Chair Dr. Charles Parkos. Graduates received their certificates of completion as they prepared to move into the next phase of their careers [...]
The Department of Pathology is set to participate in the Michigan Medicine Youth Summit on Saturday, May 21, 2022 at the Big House in Ann Arbor [...]
The role of artificial intelligence (AI) in healthcare continues to expand. In a recent issue of BMC Cancer, Dr. Vipulkumar Dadhania (first author) and colleagues published a result of their study Leveraging artificial intelligence to predict ERG gene fusion status in prostate cancer. The expert team from the Michigan Center for Translational Pathology developed a deep-learning-based model to predict ERG genomic rearrangements in prostatic adenocarcinomas using only H&E-stained digital slides [...]
This year's Medical Laboratory Professionals Week celebration at the Department of Pathology, which ran from April 24-30, 2022, was a big success! Let's take a moment to recap some of the top moments...
Congratulations to Dr. Kristina Davis, who was just elected Co-Chair of the Transplant Diagnostics Community of Practice (TxDxCOP) for the American Society of Transplantation (AST). Davis will assume her position as Co-Chair at the Amertican Transplant Congress meeting in Boston this June. She is replacing Dr. Evan Farkash, who will serve as Chair of this committee [...]
Drs. Liron Pantanowitz, Jeffrey Myers, Priya Kunju, as well as David and Elle Chapel were featured in the April 2022 edition of CAP Today Magazine, a medical science publication by the College of American Pathologists. The article focuses on the development of the AP hospitalist role at Michigan Medicine [...]
This month marked the usual United States and Canadian Academy of Pathology (USCAP)'s Annual Meeting. This year's hybrid-style event, the 11th annual, was held both in-person and virtually in Los Angeles, California from March 18-24, 2022. The symposium featured several short and long courses, as well evening specialty conferences and ticketed seminars. The conference also included numerous poster sessions, live Q&A segments, and a multitude of social events [...]
Today is Match Day! Match day is when medical students find out where they will be going for their residency training programs and the training programs find out who is coming. In this year’s match, the Department of Pathology discovered that the following medical students will be coming to Michigan on July 1, 2022 [...]
Dr. Riccardo Valdez, the John G. Batsakis Professor of Pathology and Director of Clinical Pathology, has been appointed as the Ambulatory Care Clinical Chief (ACCC) for Pathology. While he has been fulfilling the duties of the role since just before the COVID-19 pandemic, the appointment was recently formalized.
Each year, thousands of pathologists assemble in person or remotely to participate in the United States and Canadian Academy of Pathologists Annual Meeting. Likewise, each year, the Department of Pathology at the University of Michigan is very well represented! This year, our faculty and trainees will be giving presentations, teaching courses, moderating panel discussions, participating as panelists, and presenting their research in poster sessions, for a total of 69 activities [...]
Please join us in congratulating Dr. Abhijit Parolia on being selected for the 2022 Harold Weintraub Graduate Student Award. The award, established by the Fred Hutchinson Cancer Research Center, is given yearly and recognizes outstanding achievement during graduate studies in the biological sciences [...]
On Monday, February 14, members from the Department of Pathology, including Tamara Kutter, Caryn Crane, Avery Polk and Jenny Fossum, teamed up to host a Random Act of Kindness event at the University Hospital. The afternoon entailed a giveaway of carnation flowers for Valentine's Day [...]
The Royal Swedish Academy of Sciences, which also awards the Nobel Prizes, announced today that Arul Chinnaiyan, MD, PhD, S.P. Hicks Professor of Pathology and Urology at Michigan Medicine and Director of the Michigan Center for Translational Pathology, has been selected as [...]
"I am very appreciative of the opportunity to work as the Residency Program Administrator in Pathology at the University of Michigan,” stated Laura Jacobus. “I graduated from the University of Michigan Dearborn and always wanted to work for U-M. I am happy and excited to be here.” Jacobus previously worked as a Residency Program Coordinator at [...]
Learn more about what it takes to be a Medical Examiner Investigator (MEI) within the section of Autopsy and Forensic Pathology.
On January 21, 2022, the Department of Pathology will bid a fond farewell to long-time staff member, Alan Machcinski. Alan joined the Department of Pathology in September 1974, working in our microbiology lab, where he performed microbial susceptibility testing. With a degree in philosophy, Alan never intended to spend his career in the department. But like many others, once he joined our team, he never left [...]