Research by Drs. Alexander Taylor and Stephanie Skala seek to understand why tumors masquerade as forms of type-2 papillary of renal cell carcinoma. The study was just published in Urologic Oncology's ScienceDirect [...]
Research from the Department of Pathology was just published in the Archives of Pathology and Laboratory Medicine. Learn more about this publication, which highlights GI samples from COVID-19 patients, led by Dr. Maria Westerhoff [...]
A research effort by Drs. Jolanta Grembecka and Tomasz Cierpicki was just published in Nature Communications. Learn more about the protein made by the ASH1L gene, which plays a key role in the development of acute leukemia, along with other diseases [...]
Research from the Department's Lombard Lab was just published in the Journal of Clinical Investigation. The study, which focuses on how the deacylase SIRT5 compound supports melanoma viability by influencing chromatin dynamics, was led by Dr. Lombard [...]
Congratulations to Arul Chinnaiyan, MD, PhD, who was announced as the Science of Oncology Award and Lecture recipient by the American Society of Clinical Oncology (ASCO). As part of this award, Chinnaiyan will present a 30-minute lecture entitled “Exploring Precision Oncology: from Gene Fusions to Related Genetic Drivers“ at the ASCO Annual Meeting, to be held virtually on June 4-8, 2021 [...]
Learn more about pathologists' attitudes toward patient interactions in this new publication, led by Dr. Cathryn Lapedis.
The department has navigated an unprecedented workload over the past year and continues to increase. Hear from experts Christine Kizer, Dr. Michael Bachman, Jennifer Bergendahl, and more, as they discuss how efforts have helped Michigan Medicine stay afloat during the COVID-19 pandemic [...]
A new publication from the Department of Pathology, led by Dr. Kathleen Cho, was just published in the American Association for Cancer Research's flagship journal. highlights how altering the microbiome within a mouse model of oviductal high-grade serious carcinoma can inhibit tumorigeneis [...]
Dr. Laura W. Lamps, the Godfrey Dorr Stobbe Professor and Director of Gastrointestinal Pathology and the director of the GI Pathology Fellowship Program, can now add President of the United States and Canadian Academy of Pathology (USCAP) to her list of titles. Dr. Lamps assumed this leadership role on April 1, 2021 [...]
This year's Medical Laboratory Professionals Week (MLPW) kicks off from April 18 until April 24, 2021. The department plans to celebrate with virtual events and activities for all those within the department! When did it start, and how can you be a part of it? Continue to the article for more information [...]
Research by Drs. Ann Laszczyk and the Department of Pathology's Dr. Gregory Dressler was just published in the Journal of the American Society of Nephrology. The study focuses on PAX2 proteins and their effects on kidney function and development.
The Department of Pathology was well represented at the 110th Annual Meeting of the United States and Canadian Academy of Pathology (USCAP), held March 13-18, 2021. This year's event was reconstructed into a fully virtual format in response to the COVID-19 pandemic, with participants able to tune in and contribute from all over the world. Several of our faculty and trainees were featured at this year's conference. Let's take a moment to recap some key highlights from #USCAP2021.
Dr. Mehra discusses his career path and how he arrived at Michigan Medicine in our latest Careers in Pathology video.
A series of sophisticated processes are required in the development of innate lymphoid cells (ILC) for them to reach maturity. The Kim laboratory discovered that basic leucine zipper ATF-like transcription factor (Batf) regulates the production of ILC progenitors in the bone marrow as well as the maintenance of ILCs in the periphery. These cells are strategically distributed in peripheral tissues to provide important innate immunity to fight pathogens such as pathogenic viruses and bacteria.
A collaboration between the Department of Pathology and the Department of Dermatology examined biomarkers of outcomes in 346 cases of Merkel cell carcinoma (MCC), an aggressive type of skin cancer. The study was published in the recent edition of Clinical Cancer Research [...]
A new publication, generated by Department of Pathology faculty members Drs. Aaron Udager and Scott Tomlins was successfully published in European Urology. The research highlights a longitudinal cohort study centered around the serial molecular profiling of low-grade prostate cancer in order to better assess tumor upgrading [...]
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Join #UMichPath and SOPHiA Genetics for a virtual event with department faculty Dr. Noah Brown, who will be hosting a discussion related to developing an NGS solution in order to keep pace with the ever-evolving recommendations and clinical guidelines for myeloid malignancies.
Technological advances have made telepathology a reality for many pathologists, allowing challenging case consultations regardless of where the expert may be located. Recently, Dr. Liron Pantanowitz, Director of Anatomic Pathology, presented a keynote address entitled, "Telepathology: Still the #1 application of digital pathology" at the 7th Digital Pathology & AI Congress: Europe, December 1, 2020.
A new study by the University of Michigan's Rogel Cancer Center analyzed patients with cancer and the factors that cause the cancer to spread to the liver, leading to worse outcomes.
Clinical trials underway are testing whether drugs that target the androgen receptor – successful in controlling prostate cancer – could also work against the coronavirus. wo proteins, ACE2 and TMPRSS2, help the coronavirus gain entry and replicate within cells. TMPRSS2 is well-known to Arul Chinnaiyan, MD, PhD. His lab discovered that TMPRSS2 fuses with the ETS gene to drive more than half of all prostate cancers [...]
Recently, Department of Pathology faculty member Dr. Laura Lamps appeared on the December 3 episode of the PathPod Pocast's Beyond the Scope. In the episode, Dr. Lamps discusses a varierty of topics including her role as the Director of Gastrointestinal Pathology at Michigan Medicine, her involvement in United States and Canadian Academy of Pathology (USCAP), personal hobbies and her experience working in medicine overall [...]
A new study led by Drs. Jolanta Grembecka and Tomasz Cierpicki of the Department of Pathology was just published in Blood's American Society of Hematology. The research focuses on combinatorial treatment with menin and FLT3 and how inhibitors induce complete remission in acute myeloid leukemia (AML) with activating FLT3 mutations [...]
New research by the Department of Pathology was recently published in Modern Pathology. The study, led by Drs. Aaron Udager, Noah Brown, Bryan Betz, Jonathan McHugh and Scott Tomlins, focuses on how TP53 mutations and CDKN2A mutations and deletions are highly recurrent molecular alterations within malignant progression of sinonasal papilomas [...]
Congratulations to Dr. Celina Kleer who was awarded the American Society for Investigative Pathology (ASIP)'s 2020 Outstanding Investigator Award. Dr. Kleer receives the award for her demonstrated excellence in research in experimental pathology [...]
Introducing the 2020 Global Virtual Cancer Conference. Join us for the segment entitled "Prevention, Diagnosis and Me" to hear from the Department of Pathology's own Dr. Jeffrey Myers, who will discuss his experiences working in the cancer community [...]
Research by the Department of Pathology's Drs. Richard Miller and Joseph Endicott was just published in the Journal of Cell Biology. The study focuses on the inhibition of class I PI3K and how it enhances chaperone-mediated autophagy (CMA) [...]
Congratulations to Dr. Jeffrey Myers, who was recently selected by Michigan Medicine for the 2020 Jack Billi Award for Inspiring Quality Improvement. Dr. Myers was selected for his exemplifying behaviors of an effective improvement leader and for using LEAN design principles and tools in his daily work [...]
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Join #UMichPath and the University of Pennsylvania's Perelman School of Medicine for a virtual event with department faculty Dr. Gabriel Nuñez, who will be hosting a discussion related to host-microbiota interactions in modern health and disease.
Congratulations to Don Giacherio, PhD, who retired July 31, 2020, following 38 years of service in the University of Michigan Department of Pathology. Giacherio completed his PhD at the University of Illinois in 1980, followed by a 2-year postdoctoral fellowship at Mayo Clinic. In 1982, Giacherio joined the University of Michigan Department of Pathology as an Instructor in Pathology [...]
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Join us for a virtual event featuring the Department of Pathology's Dr. Celina Kleer, who will host a discussion related to her experiences in understanding breast cancer and her journey as a physician-scientist.
New research from the Department of Pathology and Dr. Alexandra Hristov was just published in the Journal of Cutaneous Pathology. The study focuses on the kappa and lambda immunohistochemistry in situ hybridization of atypical cutaneous lymphoid infiltrates.
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Join us for a virtual event featuring the Department of Pathology's Dr. Arul Chinnaiyan, who will give the 2020 American Society for Investigative Pathology (ASIP)'s Rous-Whipple Award Lecture.
The University of Michigan will begin a Sampling and Testing Program of asymptomatic students, faculty and staff for the virus that causes COVID-19 on September 7.
Dr. Celina Kleer named 2019 AACR Outstanding Investigator in Breast Cancer Research
On Friday, June 19, the Department of Pathology hosted an Equality Walk at NCRC `in observance of the Juneteenth holiday. Here, members from all areas of the department gathered to show their support against racial discrimination and for the Black Lives Matter movement.
Dr. Jeffrey Myers discusses the importance of frontline workers and their caring of patients - alive or deceased - during the COVID-19 pandemic.
The protein Argonaute 2 was found to be critical to the progression from benign lesions into pancreatic cancer, suggesting a therapeutic opportunity.
Congratulations to Arul M. Chinnaiyan, MD, PhD, on his election to the National Academy of Science! Chinnaiyan is an investigator, Howard Hughes Medical Institute; and S.P. Hicks Endowed Professor of Pathology, American Cancer Society Research Professor, and director, Michigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor [...]
Congratulations to Alex Taylor, MD, 3rd year resident, for winning the first place Rodger Haggitt GI Pathology Award for his platform presentation at USCAP!
Sara Abbott, MD, took a winding road to becoming an assistant professor here at U-M. She actually has a master’s degree in education and spent two years guiding students grudgingly through high school biology. That’s when she realized that maybe this wasn’t the kind of teaching she was meant to do after all. [...]
Marcin Cieslik, Assistant Professor of Pathology and Computational Medicine and Bioinformatics and member of the Michigan Center for Translational Pathology (MCTP), received an award from Bristol-Myers Squibb (BMS) for the project entitled, “Identification of novel therapeutic vulnerabilities across immunophenotypes of refractory and metastatic tumors.” This award provides two years of funding.
Nicholas Lukacs, PhD, The Godfrey Dorr Stobbe Professor of Pathology, received an Outstanding Investigator Award (OIA or an R35) from the National Heart, Lung, and Blood Institute (NHLBI) entitled, “Viral and allergen-driven immunity in chronic lung disease.” This award will provide 7 years of funding. [...]
PTM Therapeutics, Inc. celebrated on February 6th the signing of an exclusive license for an antibody (PTM-001) jointly from the University of Michigan and Emory University during a bell-ringing ceremony at University of Michigan Tech Transfer. The startup is [...]
Vipulkumar Dadhania, MBBS, is fascinated with learning. It’s this passion that will keep him evolving in his career. He joined U-M in August of 2019 as a clinical assistant professor in the Department of Pathology. His primary interests are genitourinary pathology and breast pathology. [...]
After a nationwide search, Allecia (Lisa) Wilson, MD, has been named the new Director of Autopsy and Forensic Services. Wilson follows the leadership of Dr. Jeffrey Jentzen. In addition to this new role, Wilson serves as Residency Program Director [...]
Modern Pathology recently published a multi-institutional study led by pathology faculty Dr. Rohit Mehra; other participating centers included The Cleveland Clinic, Emory School of Medicine and Memorial Sloan Kettering Cancer Center. Third year Pathology resident at Michigan Medicine, Alex Taylor, MD, was the first author with other major contributions by Drs. Noah Brown and May Chan. [...]
It is with great sadness that we announce the passing of Mila Blaivas, MD, PhD. Blaivas passed away after a short illness on January 6, 2020, at a local hospital in Salt Lake City, Utah, where she had moved to be with her daughter and son-in-law in May 2011. She is survived by her husband, Dr. Alex Blaivas, who was the love of her life, two children and three grandchildren.
It is with great pleasure that we announce Dr. Rajiv “Raj” Patel as our new Section Head (Director) for Dermatopathology effective February 1, 2020. [...]
In 2015, Felipe da Veiga Leprevost, PhD, came to the University of Michigan as a research fellow to study computational proteomics. In June of 2019, he accepted a faculty position as a Research Investigator in Bioinformatics. He now has a Michigan-born little one and his roots are growing deeper in Ann Arbor [...]
The National Association of Medical Examiners met recently in Kansas City, MO, for their annual conference. University of Michigan forensic pathologist, Milad Webb, MD, PhD, presented on the critical national shortage of forensic pathologists, as well as pathologists in general [...]
The Dean’s Awards Program recognizes Michigan Medical School faculty and staff who demonstrate exceptional accomplishment in the areas of teaching, research, clinical care, community service, and administration. This year’s honorees were honored November 13, 2019 at the annual Dean’s Awards Dinner. [...]
Dr. Gabriel Nuñez, the Paul de Kruif Endowed Professor of Pathology, is one of the newest members of the National Academy of Medicine. The Nuñez laboratory has made ground-breaking discoveries in the field of [...]
Congratulations to Steven L. Kunkel, PhD, on his appointment as the executive vice dean for research and chief scientific officer of the University of Michigan Medical School, effective September 1, 2019, following a nationwide search for the best candidate. Kunkel previously served [...]
Laurie McCauley, DDS, MS, PhD, received the 2019 Stephen M. Krane Award on September 20th, 2019. The American Society of Bone and Mineral Research (ASBMR) gives the award in recognition of outstanding achievements in basic, translational, or clinical research in inflammation and/or skeletal matric biology [...]
The third edition of Diagnostic Pathology Gastrointestinal has been released. The textbook, authored by the Department of Pathology's Joel Greenson and Scott Owens, is an award-winning volume in the Diagnostic Pathology series. This one-stop reference for [...]
A U-M study is the first to define how a little-known type of cell death impacts tumor cells and immune cells.
University of Michigan researcher Lee Schroeder takes a deep dive on much-needed help for tackling the burden of cardiovascular diseases in India.
The Department of Pathology was well-represented at the American Society for Investigative Pathology’s 2019 Annual Meeting.
The Fifth Edition of Histology for Pathologists has just been published by Wolters Kluwer and Maria Westerhoff, MD, and Joel Greenson, MD, co-wrote the chapter on colon histology. The newest edition of this award-winning book is a comprehensive collection of normal histology written by anatomic pathologists for anatomic pathologists. The book is designed to [...]
Dr. Charles Parkos, Carl V. Weller Professor and Chair of the Department of Pathology, has been inducted into the Association of American Physicians (AAP). Founded in 1885, the AAP is an organization of leading senior physician-scientists [...]
Dr. Rajiv Patel, along with Dr. Steven D. Billings and Dr. Darya Buehler, has edited the textbook, Soft Tissue Tumors of the Skin. A useful tool for daily sign-out, the beautifully-illustrated book outlines
Dr. Kathleen Cho received a five-year R01 grant from the National Institutes of Health (NIH) to continue her work in ovarian cancer research. High-grade serous carcinoma, or HGSC, is both the most common and most deadly form of “ovarian” cancer, although it is now believed that most HGSCs arise [...]
On December 12, Dr. Thomas Glover was recognized as the recipient of the 2018 Distinguished Faculty Lectureship Award in Biomedical Research. Glover, who is the pioneer and defining scientist in the field of common fragile sites (CFS) in human chromosomes, gave [...]
Tomasz Cierpicki, PhD, has been awarded an RO1 with five years of funding from the National Cancer Institute for his grant application, Targeting NSD1 In Leukemia, to develop inhibitors of NSD1 histone [...]
Jiaqi Shi, MD, PhD, has been awarded a KO8 (Career Development Award) from the National Cancer Institute for her grant application, Linking epigenetic regulation and TGF-β signaling in [...]
Precision Health at the University of Michigan has chosen Dr. Jeffrey Hodgin as one of ten recipients of its Investigators Awards. The grants, totaling nearly $3 million, are of up to $300,000 each [...]
The Fourth Edition of the World Health Organization (WHO) Classification of Skin Tumours has been released. Edited by David E. Elder, Daniela Massi, Richard A. Scolyer, and Rein Willemze, the book contains content contributed by the Department of Pathology’s [...]
The board of regents has appointed Steven Kunkel, PhD, as the interim executive vice dean for research and chief scientific officer [...]
Funding to Chinnaiyan supports evaluating new cancer markers that could become treatment targets.
The textbook, Atlas of Non-Gynecologic Cytology, has been released as part of the Atlas of Anatomic Pathology series. The book was edited by U-M’s Associate Professor of Pathology, Xin Jing, MD, as well as [...]