Kristina Martin, MLS(ASCP)CH will present Document Control for Control Freaks during the Biomedical Laboratory Diagnostics (BLD) Seminar Series at Michigan State University. The series, celebrating its 90th year, invites BLD alumni to share educational lab topics and insights from their careers in health care. Kristina’s presentation is on Tuesday, February 28 at 4:00pm EST in North Kedzie Hall, room N317.
Congratulations to Molecular and Cellular Pathology PhD student, Hung-An (Ana) Ting, in the laboratory of Dr. Nickolas Lukacs, whose work on “Notch Ligand Delta-like 4 Promotes Regulatory T Cell Identity in Pulmonary Viral Infection" is featured in the “In This Issue” section of the February 15, 2017 issue of The Journal of Immunology. The “In This Issue” highlights articles considered to be among the top 10% of articles published in the journal. Their work is on regulating lung pathology with the Notch pathway.
Assistant Professor of Forensic Pathology and Director of the Residency Training Program, Allecia Wilson, MD has been named President of the Michigan Association of Medical Examiners (MAME). MAME's mission is to foster the highest professional standards in the performance of the duties of the county medical examiners of Michigan. [ ... ]
The laboratory of Dr. Celina Kleer, Harold A. Oberman Collegiate Professor, isolated human mesenchymal stem cells from breast cancer metastasis. The lab discovered that a collagen receptor tyrosine kinase, DDR2, mediates stromal-cancer communication and induces breast cancer metastasis. The study provides the basis for the development of DDR2 inhibitors. The article appeared in Cell Reports and can be found at www.cell.com.
Effective December 20, 2016
The manufacturer of the chemistry analyzers and reagents used here at UMHS (Siemens Healthineers, Tarrytown NY) has recently announced a change in its calibration material for the direct bilirubin assay in order to bring results more in line with a reference method. [ ... ]
Kudos to Chemical Pathology’s Nick Wesener, MLS (ASCP)cm, Senior Clinical IT, POC for being selected to serve on the Alere Informatics RALS Advisory Board (RAB). The purpose of the RAB is to facilitate transparent discussion between Alere Informatics and the point-of-care testing community. Topics include issues and trends that may influence the way RALS Point-of-Care Data Management Systems programs are managed. Those selected to serve on this board are considered leaders in the field of point-of-care testing who can provide valuable feedback to Alere Informatics and experience and knowledge to other RALS users.
Mary Skinner serves as the lab manager for David Lombard, MD, PhD. In addition to managing the animal colony, maintaining and allocating funding, and performing her own research, she trains new team members, reminding them that as science changes the lab needs to change with it. Learn more about what makes Mary deserving of the nomination, including her mantra for the success of the lab, by reading more in this story from UMHS Headlines.
The laboratory of Dr. Celina Kleer, Harold A. Oberman Collegiate Professor, discovered that mammary-specific knock down of CCN6 results in mammary carcinomas with features of human metaplastic carcinomas. This model may lead to discovery of new diagnostic and therapeutic targets for this rare and aggressive form of triple negative breast cancer. The article appeared in Oncogene, on the November 7th 2016 issue, and can be found at www.nature.com
Laura Lamps, MD will join the Department of Pathology as the Director of Gastrointestinal Pathology on February 1. Dr. Lamps comes from the University of Arkansas for Medical Sciences Center where she was the Director of Surgical Pathology, Director of the Diagnostic Laboratories, and Professor and Vice Chair of Academic Affairs for Pathology. [ ... ]
Dr. Stephanie Skala received the 2nd place prize in the Resident Research Competition at the recent Michigan Society of Pathologists' Winter MSP Conference on November 12, 2016, in Dearborn, Michigan. [ ... ]
The laboratory of Dr. Tomasz Cierpicki has determined the structure of BMI1 protein in complex with PHC2 and characterized its role in regulation of the architecture and activity of the PRC1. The article "BMI1 regulates PRC1 architecture and activity through homo- and hetero-oligomerization" has been published in Nature Communications. Co-first authors are Felicia Gray, Hyo-Je Cho and Shirish Shukla, and this is a collaborative study with Dr. Grembecka and Dr. Lawlor from the Department of Pathology.
Dr. Geoff Baird from the University of Washington came as a Visiting Professor to the Department of Pathology on October 17th. His lecture and interest is “Laboratory Test Utilization Management: What Works, and What Doesn’t”.
Congratulations to the Nusrat/Parkos Lab on having the cover image of the September 2016 issue of Mucosal Immunology. The image is from their article, Neutrophil interactions with epithelial expressed ICAM-1 enhances intestinal mucosal wound healing.
You can read more at nature.com.
A team of twenty, including Assistant Professor of Pathology, Scott Tomlins, M.D., Ph.D. is launching a Blood Profiling Atlas pilot as part of the Cancer Moonshot initiative. Led by Vice President Joe Biden, the Moonshot strives to end cancer as we know it.
Click to read more about Tomlins’ roll in this mission.
Effective immediately, Dr. Allecia Wilson is the Program Director for the Anatomic and Clinical Pathology Residency Program. Dr. Wilson completed residency here at Michigan, followed by Forensic Pathology and later Pediatric Pathology fellowships. Since returning to our Department in 2012, Dr. Wilson has been recognized as a talented and devoted teacher of residents, fellows, and medical students. [ ... ]
Congratulations to Eric R. Fearon, MD, PhD, who has been named director of University of Michigan Comprehensive Cancer Center. Dr. Fearon's research focuses on the field of cancer genetics, specifically colorectal tumors. He has authored more than 135 peer-reviewed research manuscripts and more than 60 book chapters and review articles. [ ... ]
The American Society for Clinical Pathology (ASCP) annually recognizes two Residents from the Resident Representative Network with the Resident Representative Leadership Award. One of the 2016 recipients is House Officer III, Stephanie Skala, MD. Stephanie received the award for demonstrating outstanding leadership and for promotion of ASCP resident activities and membership. Congratulations, Stephanie!
Congratulations to the Department of Pathology's David Manthei, MD, PhD, House Officer III, for winning the "Best Poster Award" at the 2016 ASCP Annual meeting in Las Vegas. His poster on "Predictive value of hypogammaglobulinemia in monoclonal gammopathies detected by reflex immunofixation of serum protein electrophoresis samples" presented the largest study to date on the value of reflexing hypogammaglobulinemic samples for detecting monoclonal gammopathies. Scoring for the award was based on originality, potential importance, research design or implementation and interpretations.
Each year, The American Society for Clinical Pathology (ASCP) awards exemplary medical students at schools in the United States, Canada, and Puerto Rico, with the Academic Excellence and Achievement Award.
Awardees are determined based on their excellence in academics, leadership ability, and a strong interest in the pathology profession.
The top award this year, the ASCP Medical Student Academic Excellence and Achievement Gold Award, was given to one of our new first year residents, Emily McMullen, M.D.! Congratulations Emily!
Congratulations to the Department of Pathology's Mike Bachman, MD, PhD, for his recent paper in the journal mBio about the bacteria Klebsiella pneumoniae, the third most common cause of infections in hospitalized patients. His work has identified siderophores, an iron-scavenging product of those bacteria, as a mechanism the bacteria use to help them invade throughout the body. Dr. Bachman is the Associate Director of the Microbiology Laboratory [ ... ]
The AMA Journal of Ethics August edition features articles on ethical issues in pathology. Current and former trainees are co-authors on these papers, including Martin Magers, John Sherbeck and Kristina Davis. Faculty members Michael Roh and Lauren Smith also contributed to this issue. Lauren Smith served as a faculty advisor to Margaret Cocks, a resident at Johns Hopkins University, who was the guest editor.
Assistant Professor Sriram Venneti, M.D., Ph.D. is one of 17 recipients of the Doris Duke Charitable Foundation’s 19th Clinical Scientist Development Awards. The awards are designed to allow junior faculty protected time for their clinical research as they establish their own research programs.
Clinical Pathology Operations Manager Kristina Martin, MS, MLS(ASCP)CM, is among one of twelve in the 2016 American Society for Clinical Laboratory Science (ASCLS) Voices Under 40 Spotlight. Awardees are scored by their peers and ranked according to their commitment to the ASCLS, their profession, and their communities early on in their professional careers. Congratulations, Kristina!
Congratulations to the Department of Pathology's Lee F. Schroeder, MD, PhD for his recent paper in The New England Journal of Medicine, Time for a Model List of Essential Diagnostics. Dr. Schroeder is part of a team working to outline the most critical diagnostic tests. The list will help standardize care, particularly in developing nations where having timely and accurate test results can significantly impact public health.
Please welcome our new fellows for 2016-2017!
Charles Harmon, MD
University of Michigan
Kristen Muller, DO
Darthmouth Hitchock Medical Center
The Wayne County Medical Examiner's office has been granted accreditation by the National Association of Medical Examiners. This is a result of the partnership between the county and the Department of Pathology. You can read about this collaboration in the most recent issue of Inside Pathology.
More than 2,500 unexpected, violent, and suspicious deaths are investigated by the team at Wayne County Medical Examiner's office each year.
Director of autopsy and forensic services at the U-M Department of Pathology, Jeffrey Jentzen, M.D., Ph.D. says, “Accreditation assures citizens and the community that the office functions at a high level and provides systematic quality and timely service.”
To hear more from Jentzen and the team at Wayne County, read the full press release.
Dr. Thomas Giordano, M.D., Ph.D, the Henry Clay Bryant Professor of Pathology, led an international study on the genomics of adrenal cancer. The project was one of the 33 projects that comprise The Cancer Genome Atlas (TCGA) project of the NCI and NHGRI. The study results were published in Cancer Cell.
Dr. Ulysses Balis, M.D., Director of Pathology Informatics, was recently quoted in CAP Todays' Newsbytes. In the April 2016 news post, Dr. Balis advises on finding, fixing, and foiling shadow IT problems based on his experience here at UMHS.
View the full article online.
The laboratory of Dr. Yali Dou, Ph.D., Associate Professor of Pathology, reported new findings in the article “PRDM16 suppresses MLL1r leukemia via intrinsic histone methyltransferase activity” which was published in the journal Molecular Cell on April 27th, 2016. Dr. Bo Zhou is the first author. Other co-authors from the Department include Shirley Y. Lee, Yuqing Sun, and Rajesh C. Rao. The article can be found online at:
Dr. Thomas Giordano is a co-author on an international study on the reclassification of a particular type of thyroid tumor which was published in the journal JAMA Oncology. This study has the potential to reduce over diagnosis and overtreatment of some patients with a particular type of thyroid cancer.
Assistant Professor, Sriram Venneti, MD, PhD, was named a Kimmel Scholar by the Sidney Kimmel Foundation. The Kimmel Scholar Awards are given annually to 15 innovative research scientists and medical doctors in the U.S. who are in the early stages of their careers. Dr. Venneti will receive a $200,000 grant for his work, titled, “Metabolic regulation of epigenetics in childhood brain tumors.” Congratulations, Dr. Venneti, on being recognized as one of the country’s most promising young cancer researchers!
Dr. David Lombard was inducted into the American Society for Clinical Investigation (ASCI).
The ASCI is an honor society of physician-scientists, those who translate findings in the laboratory to the advancement of clinical practice. Founded in 1908, the Society is home to nearly 3,000 members who are leaders in academic medicine and industry. Dr. Lombard was one of only 74 new members inducted at the annual ASCI meeting on April 15th.
Dr. Scott Owens, Associate Professor, has been selected by the Galens Medical Society to receive the 2016 Elizabeth Crosby Award, presented to a faculty member in the Medical School for outstanding teaching of medical students.
Please welcome our new Pathology Residents who will be starting in July.
Kyle S. Conway - University of California School of Medicine, San Diego
Amanda L. Kitson - University of Toledo School of Medicine
Emily R. McMullen - University of Iowa Carver School of Medicine
Chelsea M. Styles - Northeast Ohio Medical University
Steven (Burke) Van Norman - Duke University School of Medicine
Nicholas A. Zoumberos - Tulane University School of Medicine
The laboratory of Dr. Yali Dou, Associate Professor of Pathology, reported new findings in the article “MLL1 Inhibition Reprograms Epiblast Stem Cells to Naive Pluripotency” which was published as an advance online publication in the journal Cell Stem Cell on March 17, 2016. Dr. Hui Zhang is the first author. Other co-authors from the Department include Bo Zhou, Avinash K. Shanmugam, Yuqing Sun, Rajesh C. Rao and Alexey I. Nesvizhskii. The article can be found online here at www.sciencedirect.com.
Dr. Dafydd Thomas is an author of the paper, Glycogen Synthase Kinase 3 Beta Predicts Survival in Resected Adenocarcinoma of the Pancreas, which was featured on the December 2015 cover of the Journal of Clinical and Translational Research.
Click Here to view the article.
April 24-30, 2016Medical Laboratory Professionals Week (MLPW) originated in 1975 in an effort to raise public understanding and appreciation for the impact of the laboratory as it relates to a patient’s diagnosis and care. It is also critical for the public to understand the quality and professional accountability the lab has as it relates to the patient. Laboratorians play a vital role as a member of the health care team. This is also a moment for lab staff to recognize their contributions to patient care while having fun with their coworkers.
Congratulations to Dr. Asma Nusrat, Director of Experimental Pathology on her election as Vice President of the American Society for Investigative Pathology (ASIP). Her term is effective July 1, 2016 after which she will become President elect, then President on July 1, 2018. Dr. Nusrat has been a productive member of the ASIP community for over a decade participating in many program committees and task forces. Her commitment to enhance experimental pathology and translational medicine is admirable as evidenced by her work as the program committee chair for ASIP and PISA (Pathobiology for Investigators, Students, and Academicians) conference. Please join us in congratulating her on this prestigious national leadership appointment in Experimental Pathology
Description: The Department of Pathology invites applications from faculty with primary appointment in Pathology for proteomics related Pilot Projects that intend to use the state-of-the-art Proteomics Resource Facility (PRF) at the University of Michigan Medical School that is led by Dr. Alexey Nesvizhskii. Funds are primarily meant to help offset the cost of proteomic experiments, the results of which could potentially form the basis for or strengthen an extramural grant application. The grant is a cost share (2/3 funded by Department of Pathology and 1/3 by the investigator).
Who Can Apply: Department of Pathology Faculty
Applications will be accepted on a rolling basis and reviewed on a monthly basis. Applications received by Monday February 29, 2016 will be reviewed by March 8, 2016.
More information about this opportunity can be found by Clicking Here
Congratulations are extended to Dr. David R. Lucas, on his endowed professorship, the A. James French Professor of Anatomic Pathology, in the Medical School, (effective Feb. 1, 2016-Aug. 31, 2020), which received approval from the regents at their meeting on Feb. 18, 2016.
Lauren Smith was named a UMHS Hospital Ethicist effective January 1, 2016. In this role, she serves as one of eight Ethicists funded through the Office of Clinical Affairs. The Ethicists are responsible for fielding ethics consults for adult and pediatric services and conducting educational sessions for the hospital. Lauren has served on the Adult Ethics Committee since 2005 and has been the Director of the University of Michigan Medical School Path of Excellence in Ethics since 2013.
The laboratory of Dr. Gabriel Nuñez, Paul de Kruif Professor of Pathology, reported new findings in the article “NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux” which was published as an advance online publication in the journal Nature on January 27, 2016. Dr. Yuan He is the first author. Other co-authors from the Department include Dr. Melody Zeng and Dr. Dahai Yang. The article can be found online here at http://www.nature.com.
On Jan. 18, the Endowment for Basic Sciences (EBS) hosted its annual teaching awards luncheon in Palmer Commons, honoring eight outstanding faculty, including, Professor Alexey I. Nesvizhskii, for excellence in classroom teaching, mentoring, and leadership in the advancement of the teaching mission.View news post via UMHS Headlines
"The bright aseptic room smelled of Pine-Sol and bleach and overripe Camembert. A white-bearded man lay on a stainless-steel examination table, his face angled toward the skylight and the cold, cloudless morning. An investigator read from his clipboard: 61-year-old white male discharged from a Detroit hospital last night was found at home, shirtless, in a wheelchair, a .38-caliber handgun in his right hand. On his chest was a burn that appeared to be an exact match of the gun’s barrel. Carl Schmidt, the medical examiner, wiped the contact wound with a wet sponge."
Written by: Peter Andrey Smith, Reporter (The New York Times Magazine)