Molecular and Celluar Pathology (MCP) Students Siva Kumar Natarajan, Paloma Garcia, and Kelly Kennaley took earned valuable experience and took top prizes during the 4th Annual Midwest Case Competition.
Recent discoveries about how the immune system reacts to injury — and the dire consequences
if that response spirals out of control — could help improve trauma care
Dr. Charles Parkos was part of a delegation representing the Federation of American Societies for Experimental Biology (FASEB) on March 8, 2018 in Washington, D.C. to advocate for increased funding for research[...]
Richard Miller MD, PhD, has been elected into the Association of American Physicians (AAP). The AAP is a non-profit, professional organization founded in 1885 for “the advancement of scientific and practical medicine.” The Association is composed of members who are leading senior physician-scientists and are [...]
Andrew Lieberman, MD, PhD, Gerald D. Abrams Collegiate Professor and Director of Neuropathology, has been elected to serve on the Neuropathology Core Steering Committee of the National Alzheimer’s Coordinating Center (NACC). The goal of the [...]
Newborns are highly susceptible to enteric infections. It was assumed this was due to immaturity of their immune systems but new research in the laboratory of Dr. Gabriel Nunez, Paul de Kruif Professor of Academic Pathology, suggests otherwise.
Congratulations to Molecular and Cellular Pathology PhD student, Hung-An (Ana) Ting, in the laboratory of Dr. Nicholas Lukacs, whose work on “Notch Ligand Delta-like 4 Promotes Regulatory T Cell Identity in Pulmonary Viral Infection" is featured in the “In This Issue” section of the February 15, 2017 issue of The Journal of Immunology. The “In This Issue” highlights articles considered to be among the top 10% of articles published in the journal. Their work is on regulating lung pathology with the Notch pathway.
The laboratory of Dr. Celina Kleer, Harold A. Oberman Collegiate Professor, discovered that mammary-specific knock down of CCN6 results in mammary carcinomas with features of human metaplastic carcinomas. This model may lead to discovery of new diagnostic and therapeutic targets for this rare and aggressive form of triple negative breast cancer. The article appeared in Oncogene, on the November 7th 2016 issue, and can be found at www.nature.com
The laboratory of Dr. Tomasz Cierpicki has determined the structure of BMI1 protein in complex with PHC2 and characterized its role in regulation of the architecture and activity of the PRC1. The article "BMI1 regulates PRC1 architecture and activity through homo- and hetero-oligomerization" has been published in Nature Communications. Co-first authors are Felicia Gray, Hyo-Je Cho and Shirish Shukla, and this is a collaborative study with Dr. Grembecka and Dr. Lawlor from the Department of Pathology.
Dr. Thomas Giordano, M.D., Ph.D, the Henry Clay Bryant Professor of Pathology, led an international study on the genomics of adrenal cancer. The project was one of the 33 projects that comprise The Cancer Genome Atlas (TCGA) project of the NCI and NHGRI. The study results were published in Cancer Cell.
The laboratory of Dr. Yali Dou, Ph.D., Associate Professor of Pathology, reported new findings in the article “PRDM16 suppresses MLL1r leukemia via intrinsic histone methyltransferase activity” which was published in the journal Molecular Cell on April 27th, 2016. Dr. Bo Zhou is the first author. Other co-authors from the Department include Shirley Y. Lee, Yuqing Sun, and Rajesh C. Rao. The article can be found online at:
Assistant Professor, Sriram Venneti, MD, PhD, was named a Kimmel Scholar by the Sidney Kimmel Foundation. The Kimmel Scholar Awards are given annually to 15 innovative research scientists and medical doctors in the U.S. who are in the early stages of their careers. Dr. Venneti will receive a $200,000 grant for his work, titled, “Metabolic regulation of epigenetics in childhood brain tumors.” Congratulations, Dr. Venneti, on being recognized as one of the country’s most promising young cancer researchers!
Congratulations to Dr. Asma Nusrat, Director of Experimental Pathology on her election as Vice President of the American Society for Investigative Pathology (ASIP). Her term is effective July 1, 2016 after which she will become President elect, then President on July 1, 2018. Dr. Nusrat has been a productive member of the ASIP community for over a decade participating in many program committees and task forces. Her commitment to enhance experimental pathology and translational medicine is admirable as evidenced by her work as the program committee chair for ASIP and PISA (Pathobiology for Investigators, Students, and Academicians) conference. Please join us in congratulating her on this prestigious national leadership appointment in Experimental Pathology
Description: The Department of Pathology invites applications from faculty with primary appointment in Pathology for proteomics related Pilot Projects that intend to use the state-of-the-art Proteomics Resource Facility (PRF) at the University of Michigan Medical School that is led by Dr. Alexey Nesvizhskii. Funds are primarily meant to help offset the cost of proteomic experiments, the results of which could potentially form the basis for or strengthen an extramural grant application. The grant is a cost share (2/3 funded by Department of Pathology and 1/3 by the investigator).
Who Can Apply: Department of Pathology Faculty
Applications will be accepted on a rolling basis and reviewed on a monthly basis. Applications received by Monday February 29, 2016 will be reviewed by March 8, 2016.
More information about this opportunity can be found by Clicking Here
The laboratory of Dr. Gabriel Nuñez, Paul de Kruif Professor of Pathology, reported new findings in the article “NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux” which was published as an advance online publication in the journal Nature on January 27, 2016. Dr. Yuan He is the first author. Other co-authors from the Department include Dr. Melody Zeng and Dr. Dahai Yang. The article can be found online here at http://www.nature.com.
Last week we were thrilled to learn that Jeff Hodgin is this year’s recipient of the Gloria Gallo Research Award, an award given by the Renal Pathology Society in honor of one of its founding members for the most impactful research program. He received the award at the annual meeting of the American Society of Nephrology. In the words of Matthias Kretzler, Warner-Lambert/Parke-Davis Professor of Medicine and Jeff’s scientific mentor . . .
The 14th Annual Pathology Research Symposium, organized and hosted by the Pathology Graduate Student Council, and sponsored by the Molecular and Cellular Pathology Graduate Program in the Department of Pathology at the University of Michigan will take place, Thursday, Nov. 5, 2015, from 9:30am to 4:15pm at the Palmer Commons Auditorium.
The highest honor bestowed by the University of Michigan Medical School was presented to Eric Fearon, MD, PhD as he received the Distinguished Faculty Lectureship Award. Given to an extraordinary leader in research whose scientific contributions are pivotal in advancing their field of scientific knowledge, this award also recognizes excellence in teaching, mentoring and service to the institution at large.
Click Here for more info on the event.
The 2nd Annual Protein Folding Diseases Initiative Symposium, “Molecules and Machines”, was held on Friday, September 18, 2015, at the A. Alfred Taubman Biomedical Science Research Building.
The University of Michigan Protein Folding Diseases Initiative (PFDI), lead by Drs. Andrew Lieberman and Henry Paulson, seeks to connect the diverse campus-wide expertise on disorders of abnormal protein accumulation and perturbations in “protein quality control.”